Health Worlds

Myasthenia gravis is myasthenia gravis (myasthenia gravisMG) is a striated muscle neuromuscular junction point of conduction disturbances in autoimmune diseases, muscle fatigue morning to evening light or heavy rest after the cholinesterase inhibitors is characterized by often to reduce involving the extraocular muscles, muscles of mastication, swallowing, severe muscle and respiratory muscle palsy. The distribution of muscle involvement by people with time, rather than a paralysis that occurs when nerve damage in the performance of the disease should be referred to as acquired autoimmune myasthenia gravis, usually referred to as myasthenia gravis. Home Symptoms Causes examination and treatment of disease prevention induced myasthenia gravis how the article got to do? Method of treatment of myasthenia gravis (a) treatment 1. Treatment (1) the preferred solution: if after removal of the thymus can be supplemented by significant deterioration of the disease, plasma exchange and high dose immunoglobulin adrenal corticosteroids and cholinesterase inhibitors and other treatment (2) the second best solution: a serious condition can not be removed by the thymus can be used in plasma exchange or high-dose immunoglobulin therapy with adrenal corticosteroids gradual transition to the single condition improved with corticosteroids and underwent stable 2 months after removal of the thymus to maintain the original dose 2 months then a slow reduction of 2 to 4 years to the disabled (3)


three alternatives: removal of the thymus can not or refuse to critically ill patients who preferred the plasma MG .
Myasthenia gravis is an acquired systemic autoimmune diseases, occur in people aged 20 to 40, more women than men. Simply put, the pathological skeletal muscle fatigue is the most basic performance of the disease. The most common muscle to extraocular muscle involvement, manifested as ptosis, blurred vision and other symptoms, may also involve other muscles of the body appears stiff facial expression, body weakness or even breathing, swallowing and other symptoms.
In recent years, found that such treatment thymectomy for myasthenia gravis have a significant effect, but to note that in clinical work will often encountered due to improper treatment of myasthenia gravis due to recurrence or worsening of the situation in medical education network collected. A child suffering from myasthenia gravis after a standardized system of treatment, remission of MG 7 years. But time after using gentamicin eye drops keratitis, and recurrence of limb weakness gradually increased, a hoarse voice the next day, drinking water, choking, difficulty swallowing. Neural physician consultation, the diagnosis of myasthenia gravis induced by gentamicin eye drops. Immediately stop using gentamicin, the symptoms gradually ease.
[Medical Education Network finishing pm]
Friends for the cause ers to pay attention to the following, we introduce the system of drugs can lead to the above:Group: aminoglycoside antibiotics. Including gentamicin, amikacin, ethyl C shuttle vancomycin, tobramycin, streptomycin, kanamycin, amikacin and so on.
Collected Medical Education Network
Group II: tetracycline class. Including tetracycline, oxytetracycline, doxycycline, minocycline and so on. This group is usually oral tablet, commonly used in respiratory and gastrointestinal infections, increase the likelihood of myasthenia gravis induced relatively smaller.
Group III: quinolones. There Ciprofloxacin, norfloxacin, ofloxacin and so on. This group of drugs to treat the gastrointestinal tract, urinary tract infection commonly used drugs, but also evoked the possibility of myasthenia gravis.
Collected Medical Education Network
Has not been found to increase with myasthenia gravis antibiotics: penicillin, erythromycin, chloramphenicol, spiramycin, oleandomycin, Pioneer and other cephalosporin antibiotics neomycin. Therefore, we recommend use of antibiotics in patients with myasthenia gravis, the preferred antibiotics penicillin, cephalosporins and chloramphenicol.Group: Anti-arrhythmic drugs, often used to prevent and treat arrhythmia. Including procaine, quinidine, lidocaine and so on.
Group II: -adrenergic receptor blockers, including propranolol, atenolol, vinegar Dingluo Er, betaxolol, pindolol (static experience), experience Yee, timolol, etc.
Some elderly patients with myasthenia gravis is often associated with cardiovascular disease, so often used these drugs, then a neurologist should be used under the guidance.Prednisone, methylprednisolone, dexamethasone treatment of myasthenia gravis and other drugs is the most commonly used drugs. But early in the application of hormones should be closely observed changes in condition, because symptoms often a transient increase of the phenomenon, individual patients may even be a myasthenic crisis (that is, cause of respiratory muscle weakness, severe cases can cause asphyxiation leading to death) .
Proposed in the application of hormone therapy for three weeks beginning with myasthenia gravis, the best conditions in a large ventilator hospital treatment, to avoid danger.Such drugs include chlorpromazine, clozapine, Flupentixol (trifluoromethyl thiophene tons), different Kaposi hydrazine, phenyl propylamine and so on.Will directly increase the number of narcotic drugs myasthenia gravis. Muscle relaxants (curare, D-tubocurarine) can lead to respiratory muscle weakness caused by suffocation and death, is myasthenia gravis prohibited drugs; membrane stabilizer (quinine, quinidine, the urea acetyl, procaine amide), depolarizing drugs (ten a quaternary ammonium, succinic choline) and other neuromuscular blockers should be used with care at the transmission; stability, morphine, sedatives and other respiratory inhibitors should be used with caution.Flavonoids piperazine ester (urinary Ling), propantheline bromide and other antispasmodic drugs are often used to alleviate or reduce the biliary and gastrointestinal motility, with the role of anti-acetylcholine receptor, so give these drugs in patients with myasthenia gravis when vigilance.
.