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Acetaminophen overdose, the body will have some side effects. Early in the 20th century, the age of 60 have high-dose acetaminophen cause liver poisoning reported, after many of the data further confirmed the long-term use or excessive use of the drug, may cause liver cell necrosis. Excessive acetaminophen toxic metabolites generated by the same will damage the kidneys, causing renal cell necrosis, particularly in combination with sodium salicylate (aspirin), or caffeine, the more likely to damage the kidneys. In addition, toxic metabolites generated would act directly on bone marrow hematopoietic system, constitute a breach, it may induce thrombocytopenia purpura, or leukemia. Children paracetamol overdose, but also may cause symptoms of central nervous system, causing drowsiness, brain damage, neurological dysfunction and so on.
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Tips:
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The recommended acetaminophen dose: adults 1 g, 1 every 4 hours, the maximum amount for the 4 g / day; children and adolescents 15 mg / kg; 1 every 4 hours; the maximum amount is 60 mg / kg / days (7 to 12 years old the maximum dose of 2 g / day).
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Summary:
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the children to use the drug treatment of common cold and fever,


not only to care about each drug dose, but also to pay attention to each drug contained in drug ingredients. Especially in taking the children with the synthesis of acetaminophen agent must the instructions beforehand and understand the dose and then clothing.
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two or three to avoid while taking acetaminophen compound preparation, to prevent overdose.
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Although acetaminophen overdose may cause serious liver and kidney dysfunction, but as long as no excess, and soon clothing, it is still very safe and effective drug.
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parents need not therefore be too cautious, so that the children can not get sick after the timely and effective treatment.
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Text / Cui Yutao
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(This article from: Sina Family)
(Parental Park (9ye.com), child care, child care, kindergarten, baby) 6230 Previous 12 pages
Medical HEALTH "> Pharmacy subjects of drugs and medicines Summary of childhood acute acetaminophen overdose or poisoning, emergency treatment reRecommended online full collection of this Jiangpeng Yu Zhang Kemin Children's Hospital Affiliated Capital Institute of Pediatrics, 100020" Shanxi Medical Magazine: half "of 2008 Volume 37 No. 5 fast-food prizes Report Summary: hospital emergency department is to meet the 5 children with acute paracetamol overdose or poisoning cases reported below, with reference to domestic and foreign emergency processes in discussion to explore the children with acute paracetamol overdose or poisoning standardized emergency treatment. Number of pages: 2 Page Range :460-461 Keywords: Emergency treatment of acetaminophen poisoning cases reported in children with acute subject classification: R971.1 [medicine, HEALTH "Phar D nervous system d anti-inflammatory drug, anti-rheumatic drugs, anti-gout drug] R696 [medicine, HEALTH "outside SCIENCES" urology (urinary and reproductive system diseases)> urinary tract diseases] Related articles: subject
Paracetamol tablets basic information name: acetaminophen chemical name: N-(4 - hydroxyphenyl) acetamide, also known as: The hydroxyphenyl acetamide; paracetamol; acetaminophen phenol; hydroxy acetanilide; vinegar Paracetamol English name :4-Acetamino phenol; N-(4-hydroxyphenyl)-Acetamide; 4'-hydroxyacetanilide formula: C8H9NO2 Molecular Weight: 151.170 structure: see Figure
Structure CAS No. : upstream raw material: 4 - amino phenol acetic acid acetic acid acetic anhydride, hydrochloric acid activated magnesium iron sodium metabisulfite common trade name day and night, one hundred-making; shall Li Tong; acetaminophen; Tylenol painkillers ; acetaminophen; Yaws up; Tylenol; Tylenol; acetaminophen; Adams Snipes; a clear fundamental nature of Properties: prismatic crystals or white crystalline powder. No smell, taste bitter. Melting point :168-172 Boiling Point: Relative density: 1.293 (21 / 4 ) Stability: Toxicity: dissolved: soluble in ethanol, acetone and hot water, slightly soluble in water, insoluble in petroleum ether and benzene. Other properties: saturated aqueous solution pH value of 5.5-6.5. 2010 amendments to update the contents of Chinese Pharmacopoeia acetaminophen Duiyixian'anjifenParacetamol page number: Chinese Pharmacopoeia 2005 Edition two -170 [Amendment] Milestone aminophenol and other impurities to take the amount of goods, accurately weighed, add the solvent of methanol - water (4:6) into 1ml of each containing about 20mg of acetaminophen solution, as the test solution (Pro with the new system); an alternative aminophenol and amount of paracetamol reference standard, accurately weighed, add 1ml of each of these solvents are made of amino phenol containing about 1


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