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Medical newsAnonymous Original Site Updated: March 12, 2009
RENefiracetam - Alzheimer's disease and cerebrovascular disease dementia drugs, the drug on Alzheimer's disease (AD) and cerebral vascular complications of clinical therapeutic value of a good .
Nefiracetam (Nefiracetam, DM9384, DZL221) is the cyclic -aminobutyric acid derivatives, developed by the pharmaceutical company in Japan for the treatment of Alzheimer's disease and related dementia, and secondary other cerebrovascular diseases, dementia.Chemical name: N-(2,6-dimethylphenyl) -2 - (2-oxo-1-pyrrolidinyl) acetamideNefiracetam pharmacological effects of a chemical called N (2,6 twelve methylphenyl) -2- (2-oxo-1 for a one pyrrolidinyl) acetamide, acetyl cholinesterase agonist, is developed by the Japanese company's new DaiichSeiyaku pyrrole ketones drugs, the compounds can be considered abnormal acetylcholine, GABA, and monoamine neurotransmitter systems back to normal. In addition, the compounds may also promote N/L- type calcium ion channels open. This product can be enhanced through the role of the cerebral cortex and the prevention of cognitive learning and memory damage, both to improve the cerebral energy metabolism and neurotransmitter function. "Drug for Alzheimer's disease (AD) and cerebrovascular sequelae have good clinical therapeutic value. and other types of similar structure nootropic drugs compared against memory loss Nefiracetam ability, can improve the normal learning ability, causes a


variety of cerebrovascular disease are effective.
Pharmacokinetics: Clinical study: healthy volunteers a single oral dose of 10-1200mg Nefiracetam after, Cmax achieved within 2 hours. Cmax and AUC in the dose range and dose-linear relationship. The apparent CL of 5.7 to 8.4L / h. 24 hours, less than 10% of the parent drug recovered from the urine, the content can improve insulin snorting mild cognitive impairment Alzheimer statins can biochemical recurrence of prostate cancer by 30% significantly reduced Danhong injection the degree of dementia patients with vascular dementia of Alzheimer drugs - clinical efficacy and better power benefits Aricept effective treatment of elderly with mild cognitive impairment Tags: Chennai Alzheimer's disease non cerebrovascular disease dementia drugs Tell a friend Favorites Close Window on one: the new oral treatment for multiple sclerosis pull quinoline Maud
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