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News chlorpromazine on central nervous system mechanism of action of phenytoin and cli


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Answer
(1) the role of the central nervous system: the role of stability and anti-psychotic effects, antiemetic effect and body temperature regulation.
(2) the role of the autonomic nervous system: a direct relaxation of blood vessels, inhibition of the heart, inhibition of vasomotor center, the blood pressure, heart rate reflex faster.
(3) on the endocrine effects: to act on the hypothalamus causing the release of leaving lactogen secretion of milk; inhibition of gonadotropin release and delayed ovulation, inhibit the sexual cycle; can inhibit growth hormone secretion. ONLINE answer adoption rate: 22.6 01:16
Chlorpromazine and promethazine meperidine are commonly used drug among frequent combination of artificial hibernation
The main function of chlorpromazine inhibition of central body temperature regulation center there is a failure of body temperature changes with the outside world so that when the outside temperature is reduced to hibernating body temperature can also reduce the body's normal temperature is 28 ~ 30 degrees ~ Bu Xiao Zhen technetium answer adoption rate: 19.4 09:42
Chlorpromazine has antipsychotic effects and antiemetic effect of body temperature regulation, endocrine.
Artificial hibernation: Clinical with physical cooling, central inhibition of chlorpromazine and other drugs such as promethazine, pethidine mixture composed of artificial hibernation, deep sleep of patients can make hypothermia (28-32 ), organizations (in particular the brain) metabolism decreased, increased tolerance to hypoxia, and decreased response to noxious stimulation, this state is called artificial hibernation.
Also be used for adjuvant treatment of hypothermic anesthesia, and severe trauma, thyroid storm, septic shock, central high fever, febrile seizures and so on. Together answered the adoption rate: 15.2 13:06
Oral, injection are easy to absorb, but the oral absorption of irregular. Oral medications are the first of the elimination of effect, absorbed 95% and plasma protein binding, easily through the blood-brain barrier, through the placental barrier. This product is excreted very slowly, the body remaining time up to several months. The adoption rate of drug network to find answers: 35.1 15:18
Chlorpromazine can inhibit the central body temperature regulation center, people's body temperature changes with the outside world, so when the outside temperature down to hibernation temperature, body temperature also dropped to hibernating temperature, while reducing machine off tissue metabolism, hypoxia tolerance improved, reduced response to noxious stimulation to achieve a protective state! answer adoption rate of exclusive Myth: 22.7 16:38


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