14
Feb
1 What is Leukemia Leukemia is a malignant disease of hematopoietic tissue, also known as "blood cancer." Which is characterized by bone marrow and other hematopoietic tissues of a large number of uncontrolled proliferation of leukemia cells, and into the peripheral blood, and the manufacture of normal blood cells was significantly inhibited, the disease ranks first in the youth of malignant disease, the cause has still not entirely clear, pathogenic virus may be the primary factor, but there are many factors such as radiation, chemical poisons (benzene, etc.) or drugs, genetic predisposition, which may be pathogenic cofactor. According to the degree of immature leukemia cells and leukemia of natural history, divided into two major categories of acute and chronic.
Leukemia is a malignant tumor of the hematopoietic system is one of the most common malignant tumor. According to retrospective survey, the incidence of leukemia, all regions in a variety of tumors account for sixth place. Leukemia, bone marrow, spleen, liver and other organs in hematopoietic malignant proliferation of leukemic cells, can enter the blood circulation, and infiltrate into the body organs of the organizations, clinical see different levels of anemia, bleeding, infection, fever and liver, spleen, lymph node swelling Congress and the bone pain. Leukemia patients, more men than women.
It is characterized by leukemic cells in the bone marrow and other hematopoietic tissue was malignant, unlimite
d proliferation, infiltration of organizations and the body organs, have different symptoms; peripheral blood quantitative and qualitative changes in blood cells. Bone marrow can generate tens of billions per day new blood cells, most of the red blood cells. The output of the human body suffering from leukemia, white blood cells more than the actual need, and most of the white blood cells are immature, the naive cells, and its survival than normal length. Although this large number of white blood cells, however, can not fight infection like normal white blood cells that. This increase in white blood cells the body will directly affect the function of important organs, affecting the normal production of healthy blood cells. The proliferation of malignant tumor cells, inhibit the production of red blood cells and platelets to stop bleeding, not even enough normal white blood cells fight infection, it is prone to injury, bleeding, infection. 2, the major pathological manifestations of leukemia cell proliferation and infiltration of leukemia. Compared with non-specific blood and tissue lesions and necrosis of malnutrition, secondary infections. Proliferation and infiltration of leukemic cells
Mainly in the bone marrow and other hematopoietic tissues, but also other tissues
Through the above we can see that infiltration of leukemia and severe tissue organs are concentrated, destruction organizational capacity larger. Leukemia in the course of the disease, most with varying degrees of bleeding, can occur at any site, but more common in hematopoietic tissue, skin, mucous membrane, the pericardium, spleen, stomach and other central nervous system. The bleeding usually occurs in the basis of infiltration of leukemic cells. Because leukemic cell infiltration, hemorrhage, infarction, and systemic metabolic disorders, partial or entire organization can have malnutrition and atrophy and even necrosis. In recent years, due to extensive application of chemotherapy drugs and antibiotics, the autopsy pathological changes have new manifestations, infiltration of leukemic cells disappeared collapse appeared fibrin, phagocytic cells, and then fibrosis. Atrophy or fibrosis of the bone marrow can occur, some fungi, protozoa infection increased, an increase in drug-induced lesions.
Cloning is an evil nature known sexually transmitted diseases, leukemia and malignant lesions can occur in the broader context of hematopoietic stem cells, involving a number of different range. The production of malignant clone may be a variety of factors, including the original tumor virus reverse transcriptase gene activation is a major, and radiation, chemical poisons, drugs (especially alkylating agents), and chromosomal abnormalities caused by genetic factors and immune function, contributing to the emergence and development of malignant clones. Some of the hematopoietic system diseases such as myeloproliferative disease, myelodysplastic syndrome, paroxysmal nocturnal hemoglobinuria and lymphoma eventually can be turned into leukemia. 3, proliferation of leukemia cell types under the classification can be divided into myeloid, lymphocytic and mononuclear cells of three categories. Mainly as infection, fever, anemia and bleeding.
According to the degree of differentiation of leukemia cells can be divided into two major categories of acute and chronic.
Acute leukemia
Acute disease, bone marrow and peripheral blood progenitor cells in the main, if not often in the treatment of patients die within six months. According to the type of leukemia cells, clinical and divided into acute lymphoblastic leukemia (ALL) and acute non-lymphocytic leukemia (ANLL) two categories, each category there are several types. Common type at home and abroad as follows:
ANLL is divided into 8, the differential of acute myeloid leukemia type (M0), undifferentiated myeloid leukemia (M1), part of differentiated myeloid leukemia (M2), promyelocytic type (M3), granulocyte - monocyte cell type (M4), monocytic cell type (M5), erythroleukemia (M6), megakaryocyte-type (M7);
ALL into L1, L2 and L3 type, in recent years and the immunological characteristics of the cells into T, B, before B, ordinary type and undifferentiated type. Patients often sudden anemia, infection and bleeding and liver and spleen, lymph nodes, and sternal tenderness, blood and bone marrow examination can confirm the diagnosis. Efficacy has improved greatly in recent years, some patients have been cured, in addition to blood transfusion and anti-infection, symptomatic and supportive treatment, the combination chemotherapy is currently the main treatment, due to new and effective chemotherapy drugs continue to emerge, and improved methods of combination therapy, complete remission rate reached 80% or more; another differentiation inducer retinoic acid, which will enable promyelocytic leukemia cells induced maturation, a significant effect, an important discovery in recent years; bone marrow transplantation may be cured, but there are still some issues to be resolved .
Patients often suddenly felt chills, fever, headache, fatigue, exhaustion, loss of appetite, nausea, vomiting, abdominal pain, bloating, often the skin, nose, mouth, gum bleeding, severe cases may have hematemesis, hematochezia, hematuria, and fundus intracranial bleeding, and there were anemia, development is extremely rapid.
Effect depending on the type and discovery vary. The younger patients more slowly the higher rate. More slowly here refers to the patient's body no longer has cancer, bone marrow was normal. Since the 50's onwards, the chemotherapy has made significant progress, more people survive longer in the. For adult lymphoblastic leukemia (ALL), the more its slow rate of 80% -90%, and if the words of a complete cure, 40% of patients can survive 5 more years; for myeloid leukemia (AML), its more rate relief of 60% -70%, and if a complete cure, at least 20% of patients can survive for 3 years.
For patients with the disease, the most critical is to control the disease. Hospital for chemotherapy patients given high-calorie, high protein, high vitamin diet, oral hygiene, enhanced care, the sterile isolation, regular treatment to prevent infection. Leukemia patients because the small number of healthy blood cells, usually for blood and platelet transport to enhance the ability of natural immune function and hemostasis. Some patients also received other drugs to prevent transmission occurred during chemotherapy side effects such as nausea and vomiting. ALL-type patients in the hospital for several weeks until a satisfactory treatment can slow healing. To control the disease, patients should continue to receive 1 month or more time in the low dose of chemotherapy and radiation treatment to eradicate cancer cells.
For acute myeloid leukemia (AML) the best way is to extend more of its slow Lang, recovery depends on whether the success of bone marrow transplantation, bone marrow transplant tissue types must be compatible with similar genetic characteristics, usually on their family members as a bone marrow donors.
Bone marrow transplantation in three stages: preparation, operation period, recovery period. First of all cancer patients control the white blood cells, usually taken to chemotherapy, and if possible with a mechanical means to separate the cells from the blood. Operation period, the bone marrow by chemical means to clean to avoid a new phase rejection of bone marrow injection, and then about a tablespoon of receiving donor bone marrow. Recovery is the most dangerous period, the new implant has not yet begun production of the bone marrow white blood cells, patients may be due to infection at any time and death. After 2-6 weeks until the new bone marrow began to produce blood cells effectively. Bone marrow transplantation is very expensive and extremely dangerous, but it gives AML and ALL types of patients with type recurrence survival in patients with a good opportunity.
Chronic leukemia
Slow onset, early and more asymptomatic, often looking at other diseases, stumbled on a blood test, according to cell type is further divided into chronic myeloid leukemia (CML) and chronic lymphocytic leukemia (CLL) into two categories. CML often obvious splenomegaly, white blood cell count often as high as 100 ~ 200 109 / l (L), extreme proliferation of bone marrow myeloid to mature and in the late promyelocytic the main characteristic features more than 90% of Philadelphia ( ph1) chromosome. Hydroxyurea and busulfan therapy available, the recent discovery of interferon -2b has a good effect, but also to eliminate ph1 chromosome, bone marrow transplantation is expected to be cured. CML late changes can be acute, treatment with acute leukemia, but the prognosis is worse. CLL often liver and spleen and lymph nodes, white blood cell count, mostly 15 ~ 50 109 / L, extreme proliferation of bone marrow cells, mainly mature lymphocytes, often do not need early treatment, and significantly enlarged lymph nodes, anemia, thrombocytopenia, were used to reduce tumor Ning, but also radiotherapy, interferon has been found to have a certain effect. Main cause of death is bone marrow failure and infection, bone marrow failure is the performance of end-stage disease, difficult to treat, but actively prevent and control infection will extend the life.
Chronic myeloid leukemia (CML) is a more difficult one, because the disease can not control once the development is generally only survive for 4 years. Chronic lymphocytic leukemia (CLL) and often slow process of suffering for the elderly, the general treatment tends to conservative treatment. As symptoms disappear, and the kind of disease will need treatment. If the swelling of lymph nodes or other organs, through a number of oral drugs to control chemical, all CLL patients can lead a normal type of life. The development of acute leukemia in the absence of prior oral medication can be controlled effectively.
CML-type symptoms of several years, CML-type interferon in patients with ingestion, but also to a longer life span. But regardless of how to treat all types of leukemia will eventually be the development of CML to acute leukemia, so the doctor is generally recommended in patients with bone marrow transplantation. Chemotherapy for leukemia patients is the basic treatment, patients receiving chemotherapy experienced a side effect of discomfort. Many relaxation therapy - including acupuncture, massage, yoga, qigong, drug or procedure can help alleviate muscle relaxation pain and nausea caused by chemotherapy. Also note that intake of some vitamins can enhance immunity, nutrients and other medicines. 4 1 cause of leukemia. RNA tumor virus viral factors in rats, cats, chickens and cows and other animals have certainly caused by leukemia, caused by these viruses are mostly T-cell leukemia.
2. Chemical factors, some chemical substances that cause leukemia effect. Exposure to benzene and its derivatives, such as leukemia incidence among the general population. Nitrosamine substances, phenylbutazone and its derivatives, chloramphenicol, etc. The report also induced leukemia can be seen, but the lack of statistical data. Some anti-tumor cytotoxic drugs, such as nitrogen mustard, cyclophosphamide, procarbazine, VP16, VM26, have recognized the role that cause leukemia.
3. Radiation factors can be sure there is clear evidence of ionizing radiation conditions can cause a variety of human leukemia. The occurrence of leukemia depends on the dose of radiation absorbed by the body, the whole body or part of the body by the medium-dose or high-dose radiation can induce leukemia. However, small doses of radiation can cause leukemia, is still uncertain. Japanese cities of Hiroshima and Nagasaki after the atomic bomb explosion, serious radiation areas by the incidence of leukemia in unirradiated region of 17 to 30 times. 3 years after the explosion, the incidence of leukemia increased year by year, 5 to 7 years to reach peak. To 21 years the incidence rate was restored to a level close to the Japanese. Radiation workers, radioactive substances (such as cobalt -60) Regular s significantly increased incidence of leukemia. Diagnosis and treatment of radiotherapy can lead to an increased incidence of leukemia.
4. Genetic factors are chromosomal aberrations in a high incidence of leukemia among normal individuals. 5 1 clinical symptoms of leukemia, abrupt onset or slow onset of leukemia in children and adolescents more rapid onset patients. Common initial symptoms include: fever, progressive anemia, bleeding tendency or significant bone and joint pain. Slow onset of old age and some who are mostly young patients, the disease gradually progress. Many of these patients for fatigue, weakness, pale and tired after the flustered shortness of breath, anorexia, weight loss or fever of unknown origin as the first symptom. In addition, the small number of patients can be convulsions, blindness, pain, gingival swelling, pericardial effusion, paralysis of both lower extremities as the first symptom onset.
2, fever and infection
A, fever is one of the most common symptoms of leukemia can occur at different stages of the disease and then there are different degrees of heat and hot type. Heating is mainly due to infection, which angina, stomatitis, the most common perianal inflammation, pneumonia, tonsillitis, gingivitis, perianal abscess, also more common. Ear inflammation, enteritis, appendicitis, pyelonephritis, also can be seen, the infection can be severe sepsis, sepsis and so on.
B, infected with bacterial pathogens common in the early stages of disease, mainly Gram-positive cocci. Although infection is rare but often more dangerous, cytomegalovirus, measles or chickenpox virus infection complicated by pneumonia, should be noted.
C, bleeding bleeding is also common symptoms of leukemia, bleeding sites can be throughout the whole body, with skin, gum, nasal bleeding the most common, but also retinal, ear, and intracranial hemorrhage, gastrointestinal, respiratory and other internal haemorrhage. Women are also more common and menorrhagia, but the first symptom.
D, anemia can occur early, a few cases can be diagnosed for months or years before the first refractory anemia occurs later in develop into leukemia. Patients are often accompanied by fatigue, pale, heart palpitations, shortness of breath, leg swelling and other symptoms. Anemia seen in all types of leukemia, but more common in elderly patients, many patients often the first symptom of anemia.
Symptoms of chronic myeloid leukemia:
Slow onset, early often without symptoms, patients can be a very long period of time without any discomfort, usually caused by physical examination or medical treatment for other diseases, only to find blood abnormalities or splenomegaly, was the diagnosis.
With the progression of the disease, there may be fatigue, fever, sweating or night sweats, weight loss, hyperthyroidism and other metabolic performance. Sense of left upper quadrant as splenomegaly and bulge, and other symptoms of fullness after eating.
Examination can be found in patients with facial, nail bed, lips pale, most notably splenomegaly, often when the doctor reached the umbilical plane. Often lower sternal tenderness. Patients with advanced skin and mucous membrane bleeding can occur. Eyes, head, breast and other organizations, there may be painless mass.
Condition is stable, 1-4 years after entering the accelerated phase, rapid emergence of symptoms of anemia, and more. After it into acute myeloid leukemia. 6 sudden onset of leukemia symptoms of leukemia ten more abrupt onset, short duration, especially in children and young people as much.
the first symptom of fever more acute fever, can be expressed as remittent fever, missed heat, intermittent fever, or irregular fever, body temperature at 37.5 ~ 40 or higher. When cold sensation, but not shivering.
bleeding is a common symptom of leukemia. Bleeding site can be all over the body, especially the nose, mouth, gums, skin, eyes common, may also have brain, inner ear and internal organs bleeding.
early stage of anemia anemia, manifested as pale white, dizziness, palpitations and so on.
hepatosplenomegaly sexual harassment occurs hepatosplenomegaly leukemia patients, with acute lymphocytic leukemia the most significant hepatosplenomegaly.
extensive body lymph nodes lymph nodes, with acute lymphoblastic leukemia is more common, but not as acute lymphoblastic CLL significant. Superficial lymph nodes in the neck, lower jaw, armpits, groin, etc., deep in the mediastinal lymph nodes and internal organs nearby. Swollen lymph nodes generally soft or medium texture, hardness, surface smooth and no tenderness, no adhesion.
skin and mucosal lesions associated with leukemia, skin lesions manifested as nodules, lumps, rash and so on. Manifested as nasal mucosa, respiratory mucosa and oral mucosa, etc. swelling and ulcers.
arachnoid nervous system inflammation, meningitis, etc. leukocyte infiltration can occur, the performance just like brain tumors, meningitis, increased intracranial pressure occurs in patients, meningeal irritation, limb paralysis and other symptoms.
infiltration of bone and joint disease of bone and joint disease after bone and joint pain often occurs, the performance of the sternum, humerus and the shoulder, elbow, hip, knee, etc. there pain, pain, occasional pain. Many children with acute lymphoblastic leukemia of bone and joint tenderness.
Other leukemia cells can infiltrate the respiratory, digestive and urogenital systems, and orbital, lacrimal gland and eyes, etc., may present with diffuse or nodular changes in the lungs, accompanied by pleural effusion, digestive disorders, proteinuria, hematuria , amenorrhea or excessive menstrual flow, proptosis, visual acuity reduced. 7 children how to prevent the occurrence of leukemia in children is a high risk of leukemia, its causes, in addition to children's immune function is relatively weak, the interior decoration materials, harmful gases emitted, inappropriate medication, excessive preservatives in food, vegetables remnants of a large number of pesticides, fish, poultry, eggs, drugs are not overlooked factor.
How to prevent childhood leukemia, the experts made the following advice to parents: Let the fresh air when the children do more outdoor activities, to enhance immunity; usual diet in the diet with a reasonable to do to prevent the emergence of acidic endangering children's health, To guarantee food on the table again, "acid eight base"; reduce pollution of the environment in children's activities in time; children medication should be aware of safety when they are sick and should not be drug abuse without permission, children eat less processed snack foods, vegetables and fruits should be cleaned before eating, can be peeled peeled eat as much as possible. Parents who found the child with anemia, so weak, her face pale, unexplained fever, bleeding and other symptoms, they should immediately take their child to the hospital to check the blood specialist. 8 1 leukemia patients nutritional guidance, high-protein
Leukemia is the blood cells of the pathological changes caused by the body of these patients is far greater than the normal consumption of protein, only the quantity but high quality protein supplement to maintain the function of tissues and organs. Another function is to constitute the antibody protein with protecting the body from bacteria and viruses, enhance the body resistance effect. Therefore, the leukemia patients should be eating high protein intake, especially multi-use some good quality and high rate of digestion and absorption of vegetable protein and soy protein, such as tofu, soybean curd, tofu in, yuba, soy milk and so on. To supplement the body's protein needs.
Human proteins have a moderating role in the body acid-base balance, if the body's protein deficiency, it will cause the body fluid acid-base imbalance, the body becomes acidic weak alkaline environment, resulting in the human body produces a variety of endogenous diseases, including cancer place.
2, eat more foods rich in vitamin
Clinical data show that patients with malignant tumors, about 70 ~ 90% of the human body have different degrees of vitamin deficiency. Foreign Medical studies have shown that eating vegetables rich in vitamin C and fruit, can prevent the spof cancer formation. Large intake of vitamin C, can also enhance the body resistance of local and systemic immune function matrix to achieve the purpose of control and treatment of cancer. Vitamin C rich foods are rape, Brassica juncea, tomatoes, white Levin, jiucai, Levin chestnut, hawthorn, citrus, jujube, kiwi, sea buckthorn and lemon.
Vitamin A can stimulate the immune system, cancer of the active mobilization of the body, physical invasion of the body to resist disease. Vitamin A rich foods are carrots, pumpkin, alfalfa, bell pepper and spinach Levin and so on.
Can be divided into water-soluble and fat-soluble vitamins, and water-soluble vitamins have VitC and B vitamins, fat-soluble vitamins are A, D, E, K, water-soluble vitamins are easily absorbed by human body easily from the loss of body fluids, if not replenish cause vitamin deficiency. Fat-soluble vitamin, easily stored in adipose tissue and liver, excreted slowly from the bile, so too will lead poisoning. The body with vitamin supplement should be reasonable, no more and no less appropriate to add. The lack of vitamins also make the formation of acid, the body from the plant to supplement the required vitamins.
3, more intake of iron rich foods with
One of the main manifestations of leukemia, anemia, so the drug treatment at the same time, encourage patients to regularly eat iron-rich foods, such as moving peas, black beans, green vegetables, dates, brown sugar, black fungus, sesame, egg yolk.
4, Eat small meals often, easy to digest
Leukemia patients, especially in the treatment process, the digestive system will always be a number of reactions such as nausea, vomiting, abdominal distension, diarrhea and other symptoms, this time the feeding method can be taken to Eat small meals or three meals a day, the increasing number of small , high-calorie, nutrient-rich foods such as cakes, chocolate, b, kiwi fruit, fresh vegetable juices. Digestive system adverse reactions, patients should be more basic food intake to reduce gastrointestinal discomfort,
5, according to the disease symptomatic conditioning diet
Patients who have poor eating satisfaction, indigestion, it can supply semi-liquid or soft food, such as the second rice, steamed custard, yogurt, bean curd, steamed dumplings and so on, while accompanied by hawthorn, carrots and other foods consumer guide .
In short, the leukemia patients because the metabolism hyperthyroidism, low immunity, need to give high-calorie, high protein, rich in vitamins, minerals and digestible diet to supplement the body heat and the consumption of various nutrients. Particularly during chemotherapy patients often have loss of appetite, abdominal distension, diarrhea, nausea, vomiting and other gastrointestinal reactions, should pay attention to food color, smell, taste, type, to arouse the appetite of patients. In the treatment of patients with leukemia during a series of adverse reactions are caused due to acidic fluid, the digestive system, have caused damage to the immune system, change the acidification of body fluids and restore the digestive system and immune system function 9, the main treatment of leukemia following treatment of several types of chemotherapy, radiation therapy targeted therapy, Chinese medicine treatment. Part of the high-risk patients need a bone marrow transplant. The past 10 years, as molecular biology, genetics, progress in understanding of etiology and pathology of leukemia, a more in-depth, and the new therapies, the discovery of new drugs and the use of traditional Chinese medicine, the prognosis of leukemia be greatly improved. "Leukemia is an incurable disease" has become the past. Formal, systematic treatment of leukemia patients can make the most of the long-term disease-free survival, or even cured.
9.1 How to choose chemotherapy, transplantation, targeted therapy of acute and chronic treatment, there are some differences. First of all have to choose chemotherapy, no matter what you type, or non-myeloid myeloid, acute Ye Hao, chronic Ye Hao, the first choice is chemotherapy. Only different types of chemotherapy drugs, chemotherapy of acute leukemia with intravenous chemotherapy are, so a series of drug use softener. Treatment of chronic myeloid leukemia in the course of the chronic phase, accelerated phase, blast phase three stages take different approaches to treatment.
In addition to chemotherapy, transplantation, targeted therapy, is there an immune therapy. Interferon is part of immunotherapy. Immunotherapy treatment of an immune cell, there is a drug therapy, the treatment of immune cells is the patient's cells isolated from the blood inside, with some cytokines in vitro, it becomes a killer cells and back again input into the blood, which can identify the killer cell killing of tumor cells.
There is also a direct to patients with some immune agents, as well as interferon interleukin , etc., called immunotherapy.
On immunotherapy, we use it to treat residual leukemia cells to the killing. Chemotherapy is a major force in fighting and killing a large number of leukemia cells, immunotherapy bit like a guerrilla-like, grab the remaining cells. Targeted therapy is specific to your target, the damage to normal cells is very small in theory. As Chinese famous beach of "anti-cancer Pioneer Network" launched a special anti-cancer immune substances "chitosan" can stimulate the immune system, enhance cellular immunity, activated lymphocytes (macrophages , T cells or killer cells, white blood cells) special effects! PH value can increase people's body fluids, thus creating an alkaline environment, enhance the ability to attack cancer cells and enhance the function of killing cancer cells! In the anti-tumor research, discovered and confirmed chitosan has very strong inhibition of cancer cells.
9.2 The advantages and disadvantages of chemotherapy, surgery and chemotherapy, radiation therapy is different from that of its overall treatment of the human body through the oral and intravenous administration in the body work. The cancer is a systemic disease of the local performance. The biggest threat to the patient is a diffusion and transfer. Chemotherapy for elimination of certain types of cancer or to prevent recurrence of distant metastasis has its own unique, cancer treatment an indispensable component.
Chemotherapy in cancer therapy and more extensive. Has been demonstrated, at least 10 kinds of tumor chemotherapy alone may have access to cure, such as choriocarcinoma, acute lymphocytic leukemia, testicular seminoma, some malignant lymphoma; about 20 kinds of cancer chemotherapy alone can be eased, especially for a number of systemic cancer such as leukemia, multiple myeloma, have aly metastatic spof tumor, chemotherapy can be used as the preferred treatment. In all cancer patients, more than half of the people at different stages in the course of the disease need chemotherapy; chemotherapy and other treatments match, greatly improving the treatment of malignant tumors, and effectively controlled the spof cancer and metastasis.
Chemotherapy in cancer therapy in recent years, the most improved method of treatment. However, chemotherapy often "non-clear", "regardless of the enemy" in killing tumor cells, but also destruction of the body's normal cells. Therefore, chemotherapy may be the following toxicity and adverse reactions:
1, intravenous injection of chemotherapy drugs, careless operation liquid leakage can cause local tissue necrosis and embolic phlebitis. Therefore, the staff must be very carefully and seriously to prevent it;
2, inhibition of bone marrow hematopoietic system, mainly white blood cells and platelets decreased. Before each chemotherapy, blood should be done to check if the number of white blood cells, if less than (2.5 ~ 3) 109 / L, platelets (50 ~ 80) 109 / l, should be temporarily stopped chemotherapy, and follow the doctor's prescription to use increased blood cell medicine. In addition to the original shark liver alcohol, leucogen, nucleotides and vitamins B6 and Qi tonic in Chinese medicine treatment, in recent years by engineering production of some recombinant colony-stimulating factor, obviously promote blood cell proliferation. Time after chemotherapy only use these drugs, white blood cells will not significantly decreased;
3, can be different degrees of damage to liver cells, increased alanine aminotransferase occurred, increased bilirubin, hepatomegaly, liver pain, jaundice, etc., can cause severe cirrhosis, blood coagulation disorders, so before treatment and medication process, to check liver function, timely detection of problems and timely solutions, if necessary, to stop chemotherapy;
4, some chemotherapy drugs toxic effects on the cardiovascular system, serious heart failure. Therefore, before treatment and should be checked in the electrocardiogram, abnormal immediately discontinued, and timely treatment. To have heart attack patients should avoid the use of toxic effects of chemotherapy on the heart drugs.
5, toxic effects on the respiratory system and adverse effects of chemotherapy drugs can cause acute chemical pneumonia and chronic pulmonary fibrosis, and even respiratory failure. Therefore, drugs with pulmonary toxicity (ie, respiratory toxicity of chemotherapy drugs), such as ADM and other glory, should be regularly checked during the treatment of lung conditions, the withdrawal must pay attention to follow-up. Pulmonary toxicity was found, immediately stop chemotherapy and hormone therapy;
6, urinary system, the performance of toxic effects and adverse reactions with proteinuria, little or no urine, and some occur hematuria. In order to understand the renal function before treatment and medication in the process have to be regularly checked, identify problems and timely treatment. Be more in the treatment of drinking green tea in the water and services Tonglin herbal diuretic, so that urine output per day in 2000 to 3000 ml. Experience has shown that this can reduce the toxic effects of urinary system and adverse reactions;
7, certain drugs can affect fertility, cause birth defects. During chemotherapy, male patients should be on birth control, female patients should be discontinued if pregnancy or to avoid chemotherapy resume normal reproductive function after treatment;
8, hair loss and skin reactions are not all patients would appear, even if there do not have to worry too much, because most patients after stopping off will re-grow hair, skin redness, rashes and pigmentation will be improved or disappeared ;
9, the systemic response to chemotherapy, the toxicity of the digestive system to the number of adverse reactions and the most troubled patients, such as nausea, vomiting, loss of appetite, abdominal pain, diarrhea, and oral ulcers, pharyngitis and so on.
9.3 The disadvantages of bone marrow transplantation
Difficulties in matching
Another important defect of bone marrow transplantation is the type of bone marrow for transplant for rare, because to find leukocyte antigen (HLA) matching is very difficult for suppliers of the same bone marrow. According to statistics, in masses of only about one ten thousandth.
Enormous cost
In general, the pre-transplant cabin after transplantation, for a total cost of 60 million, is generally difficult to accept patients
9.4 Chinese medicine treatment
Leukemia is a hematopoietic tissue malignancies. The disease belongs to the medicine "acute labor", "hyperlipidemia" and chronic leukemia in areas such as the liver, spleen, lymph nodes are the main symptoms and signs are mostly "Zheng Jia", "accumulation," "M. scrofulaceum" category . Chinese medicine believes that the pathogenesis of this disease a "disease because of false" and "due to illness caused by virtual" two , the former first, the disease that physically weak internal injuries, and then take care of evil; the latter that the first, the cult poison V and result in positive imaginary Xie Sheng. However, according to the clinical manifestations of this disease, most scholars believe that the disease is virtual and real and the virtual standard false certificate. Famous traditional Chinese medicine on the beach, the "anti-cancer Pioneer Network" Chinese medicine to provide the following recipe for reference:
(1) Sang Sang Tang: functional detoxification, Qi Yin. Indications of acute leukemia. The party clearing and detoxifying, nourishing effect. Both Quxie, but also righting, which is not to hurt the banishment of evil spirits, righting did not love evil, righting synergistic anti-cancer effect, it is to obtain results.
The Treatment of 120 cases of acute leukemia, 30 cases of complete remission, 25%; partial remission in 60 cases, 50%; no remission of 30 cases, 25%; the total effective rate was 75%. The patients in the 40 cases of acute lymphocytic leukemia; acute monocytic leukemia 30 cases; acute myeloid leukemia 50 cases. Some patients had used irregular chemotherapy.
(2) Angelica Chuanxiong soup: functional blood circulation. Indications of acute leukemia. Chinese medicine believes that blood stasis in the pathogenesis of this disease plays an important role. Wu used the side with chemotherapy can improve the response rate of this disease, reduce side effects of chemotherapy. Modern pharmacological studies show that traditional Chinese medicine to promote normal bone marrow hematopoietic stem cell proliferation, differentiation, maturation and release, contribute to leukemia hematopoietic function recovery after chemotherapy.
The side with the VAC - P chemotherapy treatment of 180 patients with acute leukemia, the results of 100 cases of complete remission, partial remission in 60 cases, no relief in 20 cases. On the beach by the famous Chinese medicine more than the "cancer Pioneer Network" Chinese medicine to provide the following recipe. 10 of leukemia in several nursing 1. Use of chemotherapy drugs should pay attention to
(1) control regimen, route of administration, and closely observe the toxicity of chemotherapy drugs. Intrathecal injection, the drug concentration should not be too large, the amount should not be too much liquid should slowly push in the supine position after 4 to 6 hours required in order to reduce adverse reactions.
(2) skilled puncture. Chemotherapy drugs administered intravenously, mostly. And there is a strong irritant. Drug leakage can cause local pain, swelling and tissue necrosis. Be confirmed when injected into the vein only after patency. Light may result from the decomposition of certain drugs. When required, such as methotrexate infusion dark black paper wrapped, so as not to break down drugs. Wear disposable gloves when operating the best protection against liquid contamination operator.
2. Transfusion care is an effective low bone regeneration being the inevitable result of chemotherapy. Leukemia in the treatment process often require transmission or transfusion of blood components to support treatment. Blood transfusion should be strictly system. General observation of the first 15 minutes of slow infusion, without adverse reaction, then children with age, heart and lung function, acute and chronic anemia and adjust the drip rate the degree of anemia. Blood transfusion process should be closely observed induced adverse reactions.
3. To increase nutrition, health giving high-protein diet, high in vitamins, high-calorie diet. Encourage children to eat. Food utensils should be disinfected, fruits should be washed, peeled.
4. Eliminate the psychological barriers
(1) enthusiasm to help care for children. Let older children know the importance of cherishing life, and establish the confidence to overcome the disease.
(2) to introduce parents and older children with the knowledge of leukemia. Advocacy for children has greatly improved the prognosis of leukemia. Such as acute lymphoblastic leukemia in complete remission rate of 95%, and 5 years survival of 70%, some patients have been cured. Acute non-lymphocytic leukemia in complete remission rate of initial treatment has reached 75%. Leukemia has been recognized as no longer considered a fatal disease.
(3) describes the treatment of leukemia chemotherapy is an important tool. For parents to understand the use of chemotherapy drugs, doses, side effects and possible adverse reactions (such as infection, bleeding, hematuria, alopecia, etc.). Understand the Regular tests (blood, bone marrow, liver and kidney function, cerebrospinal fluid, etc.) need, as well as the treatment of patients in which stage. So that children can actively receiving treatment, the treatment effectively.
(4) regularly hold parent seminars, so that parents of children with communication and care, treatment with the experience, about the harm does not adhere to treatment.
(5) regular meetings of party, so that parents of children with the exchange of old and new experience. Initial treatment were seen to have been cured by the health status, thereby increasing the confidence of cure. 11 of leukemia therapeutic diet prescriptions 1 fresh mushrooms cabbage dumplings
[Formula] flour, cabbage, each 500 grams, 100 grams of fresh mushrooms and spices amount.
[System of law] and the trace of flour, salt, 200 grams of water phase and, repeatedly rub into a smooth, soft dough, cover, wake up 15 minutes into the boiling water in the hot soft cabbage, chopped, and fresh mushrooms at the end mixing, add ginger , green onion, rice wine, salt, sesame oil, monosodium glutamate, modulation into the pie, the dough 60 minutes, roll skin, packets into the dumplings into the boiling water to cook.
[Effect] detoxification cancer.
[Indications] for leukemia, uterine cancer, skin cancer, sarcoma and so on.
2 Mushroom Tofu Stew
[Formula] 15 grams of mushroom, 1 small piece of tofu ham at the end, peas and spices of the amount of 10 grams.
[System of law] Tricholoma bubble open, wash, soak mushrooms, water clarification methodology; tofu cut in strips, remove and drain and scalded with boiling water. Put mushroom soup and hot pot of water boil, add mushroom, tofu, ham end, peas, salt, simmer for about 10 minutes, thicken, transferred to MSG, pour a little sesame oil.
[Usage] adorned with food.
[Effect] spleen and stomach qi.
[Indications] for lung disease, leukemia, anemia, calcium deficiency in infants and young children, iron deficiency embolism.
Mussel meat, fried garlic 3
[Formula] garlic, 250 grams of mussel meat, the garlic and spices amount
[System of law] garlic washed, cut into 2 to 3 cm long segment, mussel meat, pine shoot knife blade, boiling water, cut into pieces a little hot, add rice wine, salt with uniform stand, vegetable cooked, cool short burst Hong garlic, ginger, garlic stir fry the next half cooked, into the clam, transferred to salt, sugar, boiling water about 4 minutes, add the MSG Serve.
[Effect] Qingrejiedu, cancer diuretic.
[Indications] can be used as all the malignant tumors, leukemia, adjuvant therapy.
4 garlic tofu
[Formula] soft tofu 400 grams, 100 grams of green garlic, spices amount.
[System of law] vegetable oil pan, cool until Liucheng hot, add garlic, stir until soft segment, add chunks of tofu, while adding the right amount of fried side rice wine, soy sauce, salt, sugar and other spices, add a little water boil, hook thin qian, transferred MSG.
[Effect] tonic antidote.
[Indications] all the cancer and leukemia patients diet.
5 eggplant garlic burn
[Recipes] Garlic 25 grams, 500 grams of eggplant, salt 2 grams, 5 grams sugar, 10 grams of soy sauce, monosodium glutamate 1 gram, ginger 5 grams, very light blue 10 grams, 10 grams of dry starch, vegetable oil 50 grams, 200 grams of broth.
[System of law] torn off eggplant to pedicel, washed, cut in half, each half of the surface divided into about 1 cm wide knife crosswise, then cut into about 4 cm long, 2 cm wide, long box (deep constantly degrees). Each Garlic cut in half, will be Sheng's boil hot vegetable oil, refining to Youpao cleared, when smoke from the fire risk. After a little cooling until the oil, stir fry the eggplant into the pot one by one, down into the ginger, soy sauce, salt, garlic and broth, after boiling, simmer for 10 minutes with a slow fire, turning uniform, thrown into the green onion, sugar and starch with water tune into the sauce thicken, transferred to MSG.
[Effect] clear blood heat, qi stagnation, Lee moisture, solutions cult poison.
[Indications] for purpura, leukemia treatment.
6 toad boiled eggs
[Formula] Toad (live) an egg one.
[System of law] Toad washed, gutted, abdomen into the egg 1, suture, and cook for 30 to 40 minutes.
[Usage] eat eggs, taken daily, 7 days a course of treatment, observation of symptoms and blood, without adverse reaction, can be served.
[Effect] detoxification cancer, rousing.
[Attending] with acute leukemia.
7 Shiquandabutang
[Formula] Astragalus, Codonopsis, Poria, Atractylodes, Rehmannia, 10 grams of white peony root, angelica 5 grams, 5 grams of cinnamon, Chuanxiong, licorice of 3 grams, jujube 12, ginger 20 grams, Feed a half, the old half a duck, pork 250 grams, 250 grams of pork belly, squid 50 grams, 500 grams of bone rods, mushroom, mushrooms, bamboo shoots, peanuts, 50 grams of pepper, salt, pepper, onion festival, wine, monosodium glutamate the amount.
[System of law] to the reed head Astragalus, add water a little soaked, sliced, dried, dry brush jujube wine, chicken, duck, pork washed cuttlefish soaked, tear film (not bone), bone rods hammer broken, sliced bamboo shoots, mushrooms cut two pieces, diced mushrooms, boiling water, boil for a short under the lower pot, remove and cool. Will Codonopsis, Astragalus, jujube, peanuts, 4 flavor packets into a package of 9 Atractylodes flavor packet into a packet of use. Put the pot of cold water 6000 ml, each on a home, into the duck chicken, pork, pork pieces, squid, stick bone, the two kits, onion festival, pepper, 30 minutes after boiling. Switch to gentle heat, add wine and continue to stew soup concentrated to 3000 ml, and then reduce the fire, stew chicken, duck and overripe. Remove the cooked chicken pieces, cut long strips of duck, pork belly strips, cut into 12 pieces elbow, cuttlefish bone slices, more than 12 were served in a bowl In another pot, add bamboo shoots, mushrooms, mushrooms, pour part of the original soup, boiling, will winter bamboo shoots, mushrooms and mushroom pieces evenly on the 12 bowl. All the soup will be filtered to remove debris, into a small pot boiling, add salt, rip fine, pepper, stir well, respectively, 12 scoop into the bowl above.
[Usage] 1 day, each 1 bowl, early morning fasting food.
[Effect] Astragalus, Codonopsis, Atractylodes, Poria, licorice, jujube Bu Zhong Yi Qi, Jian Wan stomach, Angelica, Rehmannia, Chuanxiong, white peony root, squid, Fei Ji, duck, pork, peanuts, bar bone Yin blood, cinnamon and blood yang to. This product supplement qi and blood, spleen and stomach, supporting the weak.
[Attending] a long illness physically weak, yin and yang dual loss, adjuvant treatment of leukemia, leukopenia.
8 melon soup yi
[Recipes] Melon 300 grams, 30 grams of plantago meters.
[System of law] both cook 1 hour.
[Usage] Take soup, salt or sugar to taste after the Yin Tang, 1 day or every other day.
[Effect] spleen dampness, heat detoxification.
[Indications] on cellular immunity and humoral immunity are promoted, a certain anti-cancer effect, for leukemia and other cancer adjuvant therapy for immunocompromised children due to disease.
Chinese medicine prescribed by a Leukemia
Qi and Yin Deficiency card identified.
Nourishing therapies, detoxification.
Party Name nourishing decoction.
Composed of 30 grams of astragalus , heterophylla 20 grams, 15 grams of refined yellow, 12 grams Atractylodes, Poria 10 grams, 20 grams of raw land, Ophiopogon 20 grams, 15 grams of aspartame, Eclipta prostrata 18 grams, 15 grams of Ligustrum lucidum, 30 grams of Hedyotis diffusa, Scutellaria barbata 30 grams, 30 grams of dandelion, thistle 15 grams, 5 grams of licorice.
Usage Shuijianbi day one, served on the 2nd.
Governing Law: detoxification, blood circulation, nourishing yin
Viola 18, 12 Honeysuckle 15 Madder 10 Anemarrhena Ophiopogon TGP 10 littoralis 10 12 10 Dandelion annua Schisandra 8 15 10 SM 12 barbata Dioscorea bulbifera chuanxiong 10 diffusa 12 12 24 Codonopsis Astragalus 18
Modified:
(1) lead to unconsciousness by a high fever, plus buffalo 35 30 gypsum
(2) eat less, loose stools, add yam Atractylodes 15 18
(3) accompanied by swollen lymph nodes, plus raw oysters turtle 15 30 15 Algae 20 Prunella
(4) palpitations, shortness of breath, pale greenish yellow, insomnia, plus 5 cornus Zhigancao Polygala 10 10
(5) bleeding, plus Panax donkey-hide gelatin powder 8 Oujie 15 10 (molten) 12 of leukemia continued treatment after recovery Abstract: Leukemia relapse of leukemia is the key issue of rehabilitation, but also leukemia after bone marrow transplantation is one important factor influencing efficacy is life threatening in patients after bone marrow transplantation is a major problem.
Reached complete remission after treatment of leukemia patients, if in the future course of the disease appear in any of the following conditions, known as leukemia relapse:
(1) the original bone marrow cells or of the original single-child policy or the original shower baby sh 5% but <20%, after a course of treatment an effective anti-leukemia bone marrow has not yet reached complete remission standards;
(2) the Central Plains of bone marrow neutrophils (original single + baby shower + baby one or the original leaching)> 20%;
(3) appears outside the bone marrow infiltration by leukemia cells, such as green tumors, central nervous system leukemia and testicular leukemia.
The main factors of leukemia relapse following aspects:
Relaxation therapy in our clinic often encountered in some patients achieved complete remission after the end of the story on from that, no longer treated by your doctor. No regular medication, re, with the doctor less often too late to wait until the time of relapse.
Prevalence of mental and physical fatigue after the economic costs were enormous, heavy family responsibilities, therefore, eager to work in a stable condition after, to look to reduce family stress. But this time the patient is in the initial recovery period, body mass has not been fully restored, once the tired, physically and mentally exhausted, then the righteous fall, disease resistance weakened, Evils will take advantage of a comeback.
Frequent colds flu relapse of leukemia is the most common factor, therefore, some attention in the prevention of everyday life. Pay attention to weather changes, timely change of clothing, avoid the rain.
Angry and depressed mood will cause poor blood in the body run disorders, poor circulation, resulting in dysfunction of organs, disease recurrence.
Excessive eating some unscrupulous in the diet of patients that eat drink more favorable for recovery. Therefore, the lavish meals, overeating, spleen and stomach function appears overburdened.
Living is not the law of good health, "early hours, living there often," is promotion of people's lives should be the law that help to health. Today's society, fast-paced world, entertainment, nightlife, many young people were addicted to them, forget the rest, living without rules.
Over some comfort in order to maintain remission in patients with good health, they rarely go out, activity decreased. In fact, in addition to drugs, proper exercise for the recovery of immune function was to promote the role of relapse prevention to rehabilitation is also an important measure.
In addition to the factors mentioned above, there are other factors is not clear. Therefore, the rehabilitation of leukemia is related to many factors. The importance of drug therapy is no doubt, however, care is also crucial. Should be doctors, patients, families, three work together closely, in order to lay a good foundation for recovery.
Low vitamin levels, significant side effects of leukemia therapy
The latest research shows that if children with leukemia can not be an adequate intake of antioxidants - vitamins, when they received chemotherapy side effects will increase the risk.
From Columbia University, Kara M. Kelly and others in the latest issue of "American Journal of Clinical Nutrition" wrote: "Some of the changes caused by chemotherapy can activate the body's antioxidant defense system, so the diet in cancer patients a certain amount of antioxidants is very important. "
In the six-month study, researchers surveyed 103 acute lymphoblastic leukemia (ALL) patients, understand the subjects intake of antioxidants and chemotherapy side effects.
The researchers said: "According to the Third U.S. Department of Health and Nutrition Survey results, the U.S. government recommended dietary vitamin E, total class erythrophyll, -carotene and vitamin A intake in this study, by intake of those who try to achieve the above criteria were 66%, 30%, 59% and 29%. With the increase in vitamin C intake, the treatment reduced the delay, reduce side effects, shorter stay in hospital. Similarly, patients infection and other side effects with the risk of vitamin E and -carotene intake increases. In conclusion, ALL patients should receive nutritional counseling to ensure that the intake of antioxidants to needs. "[ Edit this paragraph] 13 prescription Pianfangyanfang: 125g weight Toad 15 (to the viscera washed), rice wine 1500ml. Will be placed in canopic jars of rice wine were closed toad, canopic jars and then into the steaming pot, add water 2 hours • filter out the liquid and set aside. Treatment: Adult 3 times a day ,15-30ml / times, after a meal with; child amount reduce it. With medication until the symptoms resolved. Subsequent maintenance therapy, medication and a half months of intermittent half months. Can be applied to other support during therapy.
Effect: The parties were treated with various types of leukemia (32 cases reached more than 20 days medication), overall response rate was 75% complete remission rate of 25%. One effect of acute lymphoblastic the best, complete remission rate was 33.3% overall response rate was 88.6%.
Party s: thousands of Ming: Chinese toad wine leukemia - report of 32 patients. "Traditional Chinese" (4): 18,198 Liushen (commercially available): 90-150 tablets per day (270-450mg), 3-4 times service.
Effect: the treatment of leukemia in 10 cases, of which CML7 cases, 3 cases of acute leukemia. 7 cases of CML, 1 complete remission, 1 had partial remission, 5 cases progress. The other 3 cases of acute leukemia, 1 case of complete remission AML.
Recipe: 3-6 blade root washing money. Shuijianbi 3 times a day.
Effects: 1 case of CML treatment, 25 days remission.
Party Yunnan Institute of Traditional Chinese Medicine.
All myeloid leukemia
Myeloid leukemia is a kind of whole bone marrow white blood cells, red blood cells and giant cells of three lines at the same time characterized by abnormal proliferation of leukemia, rare, and often secondary to radiotherapy and chemotherapy, and MDS. Frequent clinical manifestations of fever, anemia and bleeding. Most cases are not swollen or slightly enlarged liver and spleen. The rapid progress of the disease, poor efficacy, short survival, poor prognosis.
Test: Where has the M6 conditions, bone marrow megakaryocyte hyperplasia, up to 10 times normal or more naive, 10% of megakaryocytes, megakaryocyte variant accounted for 30%, to diagnose the disease.
All myeloid leukemia diagnosis:
1. Blood: Hb mostly moderate to severe reduction of blood film shows fine grains and nucleated red blood cells. Thrombocytopenia can also be normal or increased, but form and function abnormalities. Reticulocyte normal or increased.
2. Bone marrow: proliferation of extremely active or significant active. Red blood cell, granulocyte and megakaryocyte dysplasia and three lines at the same time accompanied by morphological changes. Immature red blood cell samples were megaloblastic changes, with multi-core, nuclear lobulation, nuclear malformation rupture transition, mitotic easy to see, was left myeloid cells, more uneven development of nuclear transfer. Megakaryocytic cells significantly increased to more than 1000 / the whole process increased the proportion of naive-type, showing that pathological megakaryocytes (eg, leaf too.)
3. Staining: nuclear red PAS (), iron stain normal.
4. Immunological tests: red line, granulopoiesis and megakaryocytic cell lines phenotype, suggesting that lesions in the early myeloid stem cell differentiation stage, is a myeloid stem cell disease. 14 leukemoid reaction of the prevention of common sense leukemoid reaction should pay attention and acute and chronic leukemia identified, under normal circumstances, this reaction mainly in the peripheral blood, and bone marrow abnormalities was not significant; some cases, blood resembles chronic myeloid leukemia, or even a considerable number of bone marrow also appeared naive cells, often misdiagnosed as leukemia. Therefore, detailed history, careful physical examination. To do bone marrow examination and peripheral blood myeloid cells differentiated alkaline phosphatase points, the main treatment is to remove the cause, treatment of their primary disease. Therefore, to seek the original disease, not to rely on quack, so as to avoid being cheated, resulting in unnecessary waste of money and mental burden.
Treatment principles: 1. On the primary disease treatment. 2. Enhance symptomatic and supportive treatment.
Medicine principles: due to primary disease specific drug different from each patient is different. According to the original aetiology, select the appropriate medication.
Additional tests: 1. Blood: red blood cells, hemoglobin can be normal (except for acute hemolytic, massive blood loss, and leukemia), platelet count normal. Significantly higher white blood cell c 25 109 / L, up to 200 109 / L, according to the different stimuli on the body have different types of leukemoid reaction, can be presented granulocytes, monocytes, lymphocytes or eosinophils cell ratio increased. Category immature cells, neutrophil cytoplasmic toxicity of particles and often occur in the vacuoles. 2. Bone marrow: hyperplasia or apparent active, no significant increase in the original cell number, and no morphological abnormalities of leukemia cells. Erythroid, megakaryocytic cell lines to normal. 3. Cytochemical staining: neutrophils was significantly higher alkaline phosphatase points. 4. Genetic screening: no Ph1 chromosome.
Chinese medicine and the role of the timing involved in leukemia
TCM treatment of leukemia have occurred in the chemotherapy response inhibition of gastrointestinal an advantage, but with the emergence of Western-related medicines; the advantages of medicine in this area gradually weakened. In recent years, with the purification of the development of technology in traditional Chinese medicine, people in traditional Chinese medicine to find a few in the clinical treatment of leukemia influential single flavor purification of Chinese medicine, such as: arsenic trioxide, vincristine and other single herb purification medicine. In the new historical conditions, how to play the strengths of Chinese medicine, identify the entry point for disease treatment, clinicians should increase as the development of modern therapeutics, updated treatment of traditional Chinese medicine and clinical thinking, fully tested and the combination of modern medicine. So as to improve efficacy, reduce the agony of patients and improve the quality of life and reduce the number of chemotherapy, to extend the time in remission after chemotherapy, further to achieve the purpose of healing.
From the large number of clinical practice, Chinese medicine, Chinese medicine as early as possible to participate in leukemia treatment can significantly improve the patient's condition. TCM qi and blood, yin and yang, the adjustment to the corresponding organs of the immune function of Western medicine. Immune status of the adjustment, Chinese medicine to improve the quality of life in patients with more obvious advantages, especially for chemotherapy patients appears low fever, sweating, bleeding, poor appetite, mental Weidun, hair loss and other symptoms, with an immediate success. Therefore, the early involvement of Chinese medicine is very beneficial to the recovery of the disease. In the current level of medical conditions the performance advantages of traditional Chinese medicine has highlighted the following points;
1, extend or stop the recurrence of leukemia. When the leukemia patients after chemotherapy, achieved complete remission or partial remission phase, the application of traditional Chinese medicine to promote the body regulating the level of recovery of immune immune function, can significantly prolong time to recurrence of leukemia or prevent a total relapse. In acute leukemia patients with acute leukemia cells in bone marrow of 30% of the proportion, the need for timely application of chemotherapy, during which Chinese medicine can be pre-adjuvant therapy to ease the application of Chinese medicine when patients can improve quality of life, delay or prevent the recurrence of Therefore, application of Chinese medicine treatment in remission of acute leukemia is the best time and the starting point.
2, control multidrug resistance, leukemia cells to chemotherapeutic drugs is tolerance, the cell itself, the rejection mechanism of toxic effects of chemotherapy drugs will soon start on the leukemic cells, especially in clinical chemotherapy, many people in the occurrence of drug resistance will appear in patients, resulting in chemotherapy can not continue effectively. Chinese medicine can restore leukemia cells to chemotherapeutic drug sensitivity, a finding that has been recognized and affirmed many scholars, led to the involvement of Chinese medicine point of the treatment of leukemia.
3, prevention of complications related to leukemia, the clinical treatment of leukemia, in the event of complications of leukemia, the treatment it is difficult, takes too amazing. Among the leukemia, in particular, need to chemotherapy were treated with combined Chinese and Western methods, to give heat, detoxification, bleeding phlegm, righting tonic, liver protection of traditional Chinese medicine dampness combined with chemotherapy significantly reduced the blood transfusion, platelet transfusion number. Application of traditional Chinese medicine, chemotherapy alone group compared with the cost of treatment reduced the overall support of 60%, and chemotherapy, the application of traditional Chinese medicine and chemotherapy alone in patients with immune function recovery to about one week in advance. Application of traditional Chinese medicine can not only reduce the physical pain of patients, but also can reduce the financial burden of patients.
4, rid the body of residual leukemia cells. Western medicine treatment of leukemia mainly chemotherapy is to kill leukemia cells, due to the dose, patients with physical tolerance, the sensitivity of leukemia cells to drug restrictions. Therefore, chemotherapy can not be 100% thing kill all the leukemia cells in vivo, residual leukemic cells are always the of relapse. To eliminate residual leukemia cells, mainly by traditional Chinese medicine. Chinese medicine because of the immune function can be adjusted to righting Quxie, detox, detoxification effect.
5, Chinese medicine can induce apoptosis of leukemia cells. Apoptosis of gratitude is to allow the growth of leukemia cells by its law of death; for the growth of leukemia cells have lost normal growth; the aging process, the so-called cell leukemia cells are immature, when the bone marrow progenitor cells, immature cells in early ratio of more than 30% of the incidence of leukemia can be diagnosed. Leukemia cells because normal cells do not have features such as the immune function of leukocytes, phagocytosis of bacteria, viruses. Genes from the human body and its regulation and control. Leukemia cells will blindly fission and proliferation of the human body will be after a certain number of symptoms, that is, the incidence of leukemia, immune regulation through the application of traditional Chinese medicine, interventional cells promote the apoptosis of leukemia in the application of traditional Chinese medicine has many advantages, such as arsenic in traditional Chinese medicine, the arsenic trioxide obtained after purification, the treatment of leukemia is well known, through modern molecular biology study confirmed that its role is to induce apoptosis in leukemia cells, so as to achieve the purpose of curing leukemia.
6. Chinese medicine can induce transformation of normal cells to leukemia, the leukemia cells that is repented of, confirmed by molecular biology, the nucleus of leukemia cells had chromosomal translocation, such as the M3, the nucleus of leukemia cells and normal cells than on chromosome , that is, chromosome 15 and chromosome 17 translocation, leading to a vicious promyelocytic clonal growth. Application of Integrated Traditional and Western treatment of the general pre-leukemia patients after chemotherapy and traditional Chinese medicine in the treatment of complete remission, the application of traditional Chinese medicine for treatment, generally 1-6 months of starting treatment, once a month Guchuan check it and if evidence of recurrence may again be used in the treatment of integrative medicine.
7. Dialectical use of Chinese herbs can reduce the side effects of chemotherapy. Among the clinical treatment of leukemia, when patients after chemotherapy by several (usually in the dose and high dose chemotherapy 3-5 times) the majority of patients with liver damage occurs, swarthy, hair loss, loss of appetite and other righteous wasting performance, this time if more chemotherapy, the patient's body can no longer afford to give up chemotherapy mean that leukemia relapse. Through clinical observation, dialectical therapy for each patient to develop individualized treatment programs so that many can no longer adhere to the chemotherapy to restore the body, and accept the treatment of Integrated Traditional and Western medicine into the difficult process of reaching prolong lives and relieve patient suffering, restore function in patients with therapeutic purposes.
8. Protection of normal hematopoietic function of bone marrow recovery, protection of other organs in leukemia chemotherapy, patients with other organ damage, or normal blood cells are particularly sensitive to chemotherapy, the dosage of chemotherapy drugs can not be forced to disable the middle of the treatment dosage and have occurred. Clinical treatment of leukemia, the use of integrative medicine approach, application of traditional Chinese medicine Liver, down yellow, blood stasis, bleeding diuretic, spleen and stomach, blood and other aspects centralizer, the patient's heart, liver, spleen, kidney, gastrointestinal conducted protection of traditional Chinese medicine to help chemotherapy patients reduce the pain, controlled clinical statistics, applied traditional Chinese medicine group and the chemotherapy alone group, patients with liver, kidney, heart, gastrointestinal reactions greatly reduced after chemotherapy in patients with physical recovery rate was significantly higher than chemotherapy alone group, the incidence of complications than in the chemotherapy group and by 50% or more.
In summary, the use of Integrated Traditional and Western treatment of leukemia, can take advantage of traditional Chinese medicine, Western medicine's strengths and complement each other, while acute symptoms, slow the root of the problem in order to obtain better clinical results.
Early comprehensive treatment of leukemia
Leukemia is a malignant disease of hematopoietic system is one of the top ten high incidence of malignant tumors. Which is characterized by bone marrow and other hematopoietic tissues of a large number of uncontrolled proliferation of leukemia cells, and into the peripheral blood, and the manufacture of normal blood cells was significantly inhibited. Leukemia, malignant diseases in young people, ranking the first, the cause has still not fully understood, the virus may be the major pathogenic factor.
Early treatment for leukemia, the clinical and more comprehensive treatment claim, which the chemotherapeutic regimens, can be combined traditional Chinese medicine to attenuated efficiency. If conditions allow, can be bone marrow transplantation, can play a radical role. Chemotherapy is an important method of early treatment of leukemia, can effectively relieve symptoms and prolong survival, and chemotherapy is a necessary step before bone marrow transplantation. In addition, IL- , LAK cells and other biological agents have a certain effect on leukemia, G-CSF, GM-CSF and other patients for bone marrow suppression after chemotherapy, can significantly reduce the inhibition of bone marrow and blood to speed up relief and reduce complications occurred. Because chemotherapy drugs have some toxicity, can be combined traditional Chinese medicine, on the one hand enhance the therapeutic effect, on the one hand to reduce the toxicity of chemotherapy drugs to enhance patient immunity.
Leukemia will not genetic?
Over 100 years ago, have been proposed in the pathogenesis of human leukemia, genetic factors may play a role. The study confirmed that genetic factors, chromosomal and gene abnormalities between the close . The occurrence of leukemia and some genetic factors, the evidence is as follows:
(1) in monozygotic twins "identical twins", the one suffering from leukemia, another chance to leukemia about 20% to 25% over the double heterozygous twins (dizygotic twins) were 12 times higher, and its main types of leukemia acute lymphocytic leukemia and acute myeloid leukemia.
(2) siblings of patients with leukemia, the leukemia incidence rate higher than the natural population of about 2 to 4 times the "10/10 million", and its type is also primarily for acute lymphocytic leukemia and acute myeloid leukemia.
(3) certain genetic diseases often accompanied by a high incidence of leukemia, the majority of these genetic diseases with chromosomal aberrations and fracture. Such as Down syndrome, chromosome 21 in three of its size, high incidence of acute myeloid leukemia and acute lymphoblastic leukemia, leukemia incidence rate of 40/10 million to 60/10 million, higher than normal children of about 15 to 20 times. In addition, Fanconi anemia and Bloom syndrome complicated by acute myeloid leukemia, ataxia telangiectasia complicated by acute lymphoblastic leukemia, Kleinefelterz syndrome "congenital testicular hypoplasia," complicated by acute myeloid leukemia.
Although the incidence of leukemia and some genetic factors are closely related, however, have seen most of the daily is not a genetic disease of leukemia.
How to combat the winter cold in patients with leukemia?
Influenza can occur throughout the year, but a higher prevalence in winter, and how prevention is essential. Experts pointed out that for the purposes of leukemia, if the cold control to do good, not even a cold, leukemia is cured in half. Prevention of cold blood can be seen how important patients.
I observed in the clinical, and some family members when patients were influenza infection, and patients themselves are not cold. This is because sick patients, the main focus is on health protection, the time and medication, reasonable arrangements for rest time, choose their own method of exercise, dietary conditioning seriously, so the effect can be achieved to prevent the common cold. So how cold prevention and treatment? We believe that traditional Chinese medicine preparation or decoction used as much as possible, because the differentiation of the targeted, can achieve good results, the purpose of side effects. For accurate treatment, as patients should at least know that "cold cold", "hot cold", "virtual cold," saying, are briefly of:
1, "cold cold" is cold cold: cold mainly for heavy, light fever, headache, stuffy nose and other symptoms. This type of flu can pass Lifei pills, taking double the dosage according to the instructions, and drink plenty of water, and then covered with blankets sweating slightly, so the cold makes the body feel evil, shed from the surface.
2, the "hot cold" that Fengreganmao: Such a cold winter, rare, but should also pay attention to the Diagnosis and Prescription. The main manifestations such as fever cold heavy, cold light, nasal congestion, sneezing, sore throat is one of the main points of diagnosis. Used this type of cold pills or West Yinqiaojiedu Ling detoxification pills, the amount of double take.
3, the "virtual cold" that is physically weak cold: this type of influenza should be worthy of further study, because the body of the individual differences, and some for the deficiency, some as Yang, and some was yin and yang, its treatment of the corresponding divided into yin, yang, yin and yang dual compensation. Specific methods, using traditional Chinese medicine professional terms, "miscellaneous ill pulse, temperature and sick tongue", that is, internal diseases clock gizzards of attention, attention to the disease like fever tongue observation. In general, red tongue without coating for the deficiency, the tongue pale Run for Yang, such as red tongu
After repeated chemotherapy, the patient decreased immune function, timely medicine, take immune therapy, nutritional support, and Western medicine treatment.
Bernie
2012/03/16 01:30
the cll internet support list home page. support for chronic lymphocytic leukemia . we invite you to become a subscriber to this unmoderated discussion list for patients, .
Day
2012/04/08 22:39
cll: chronic lymphocytic leukemia list home page
Katrina
2012/04/10 03:16
small lymphocytic lymphoma/chronic lymphocytic leukemia (sll/cll) is considered a very . leukemia recurrence is unusual and 45-65% or patients survive beyond .
Frederick
2012/05/05 18:22
tennessee oncology - small lymphocytic lymphoma/chronic .
Janet
2012/05/06 07:34
as a leukemia, cll accounts for about 30% of adult leukemias in western countries. the chronic lymphocytic leukemia research consortium has ongoing research projects in .
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