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Abstract: The purpose of achalasia is a primary esophageal motility disorders, the cause is unknown, the majority considered a neurogenic disease, and esophageal wall myenteric plexus (Auerbach's plexus) degeneration is related to patients the lack of esophageal body peristalsis, lower esophageal sphincter (LES) relaxation insufficiency. previous diagnosis mainly depends on esophageal barium meal examination, this paper achalasia esophageal manometry, and changes in the value of the diagnosis. Methods 35 patients with achalasia and 30 cases healthy volunteers. The main symptoms: 35 cases of dysphagia, reflux in 11 cases, 5 cases of chest pain, weight loss of 23 cases. endoscopy all patients, 25 patients with esophageal cavity to expand, while 11 patients with fluid retention, 30 cases of cardiac area closed, and promote a sense of resistance when endoscopy can be more successfully into the .5 cases mirror. esophageal barium performance: 32 patients have shown that when the barium blocked by cardia, upper esophagus with varying degrees of expansion, the cardia was beak-like .2 cases of esophageal barium change no abnormal findings. esophageal manometry by liquid conductivity method (apparatus were Sweden (CTD-Synectics products). determination of resting lower esophageal sphincter pressure (LESP), lower sphincter relaxation pressure (LESRP), calculated The following sphincter relaxation rate (LESRR), also measured resting upper esophageal sphincter pressure (UESP), upper e


sophageal sphincter relaxation pressure (UESRP). esophageal body peristaltic amplitude, synchronous contraction waves (partial or full synchronization of contraction) and secondary contraction wave (not swallowing the esophageal contraction wave) occurred in percentage. All data are expressed by x-s, statistical treatment using t test. Results 1. esophageal body manometry performance: 35 patients with achalasia of 100 patients with body % are synchronous contraction waves, of which 91.4% (32/35) for the low-amplitude simultaneous contraction of the Han .8.6% (3 / 35) for the normal rate of contraction wave .85.7% (30/35) also exist secondary contraction, and secondary contractions were also non-conductive contraction wave. esophageal resting pressure was higher than intragastric pressure .2. Determination of the lower esophageal sphincter: in patients with achalasia LESP was 49.041.3mmHg, significantly higher than the control 18. 74.5 mmHg (P <0.01), 82.9% (29/35) of patients with LESP was significantly higher than the control, only 17.1% (6 / 35) in the normal range. esophageal sphincter relaxation rate (LESRR) was 69.116.3% significantly lower than normal controls 96.0 0.1% (P <0.01) .3. Determination of the upper esophageal sphincter: achalasia patients with upper esophageal sphincter pressure (UES P) as 41.017.8mmHg, with no difference between the control group 39.414.4mmHg ( 0.05). Conclusions Esophageal manometry is a simple, fast and safe method for esophageal function tests can be observed in different parts of the motor function of the esophagus. achalasia, esophageal body in patients with synchronous contraction of low amplitude waves and LESRR increased, especially important to the early diagnosis and severity, diagnose the disease is a reliable method. for all suspected patients with achalasia esophageal manometry should be early, not only for early detection of disease and prognosis of help.
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