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Posted at quote 1st Floor Abstract: cats with hyperthyroidism associated with hypertrophic cardiomyopathy Beijing Yongchang Animal Hospital Guo Zhisheng hyperthyroidism is due to the circulatory system caused by high concentrations of T4 or T3 as a multi-system disease. Is the cats a common endocrine disease, hospital admissions associated with many cases of cats with hyperthyroidism hypertrophic heart .Hyperthyroidism is due to the circulatory system caused by high concentrations of T4 or T3 of a multi-system disease. Is the cats a common endocrine disease, hospital admissions and more cases of cats with hyperthyroidism associated with hypertrophic cardiomyopathy, are summarized as follows:
(A) clinical data:
Breed: cat Age: 3 Sex: Male Weight: 6.9 kg without immune
(B) of the medical record:
This is an age of 3 years Huanxu stray cats, cat, a wonderful reflection of the main complaints has been in this big belly, appetite, water quantity, the stool soft. In recent days there sneezing, drooling, panting.
(C) clinical examination:
Spirit can be, asthma, abdominal circumference large, purple hair and nose, sneezing, auscultation, tachycardia, conjunctival cyanosis. Body temperature of 39.0(E) radiographic:Case analysis and related information
. Thyroid composed by the two leaves, in normal dogs and cats are intangible. Each leaf has two parathyroid thyroid. To active absorption of thyroid accumulation of inorganic iodine, so the concentration of the


blood concentrations of 10-20 times. Inorganic iodine into the thyroid gland acinar cells, generate metabolic activity of thyroxine, the thyroxine (T4) and three iodine acid (T3). T3 and T4 synthesis and release by the anterior lobe of the thyroid-stimulating hormone cells of the thyroid stimulating hormone (TSH) control.
. Hyperthyroidism is middle aged and older cats is a common disease, average age of onset in the 13-year-old cat, ranging from the range of 6-21 years of age, only 6% of cats with hyperthyroidism patients younger than 10 years old, I sex and species tend to.
. Clinical symptoms:
excessive appetite accompanied by weight loss
a. weight loss (> 95%) b. bulimia (50%) c. the lack of caloric intake, increased energy consumption to meet the LPS thyroid disease state occurs.
behavior change:
a. exhibit hyperactivity behavior, nervousness and aggression
b. direct effect of thyroid hormone may be secondary to the behavior of the central nervous system changes.a. diarrhea or stool quantity. From the increase in food intake, gastrointestinal activity, and poor assimilation.
b. vomiting. Rapid intake of large quantities of food and stimulate the thyroid hormone receptors on the direct catalytic role in chemistry.- Serum liver enzyme activity increased renal symptoms.
a. polyuria and polydipsia syndrome
- Increased blood flow from the kidney, renal filtration rate and tubular reabsorption and increased secretionb. prerenal azotemia, or because of increased tissue catabolism associated with increased urea and creatinine
c. due to correct the hyperthyroidism, renal blood flow caused by the degradation of renal function.
skeletal system symptoms.
a. Hyperphosphatemia: the absorption of minerals from the bones to increase
b. may be derived serum bone alkaline phosphatase activity
cardiovascular system symptoms:
a. heart murmur or gallop there
b. cardiac hypertrophy
- Cardiac output, heart rate, stroke volume increased- Post to heart failure, poor prognosisb. left heart axis deviation, left bundle block after
c. Atrioventricular of pre-contraction
radiology
a. ventricular hypertrophy, pulmonary edema and pleural effusion . Laboratory
CBC results: red blood cells increased, white blood cells such as emergency
serum biochemical indicators
a. elevated liver transaminase "90%
b. increased blood urea nitrogen and creatinine, high blood sugar.
the concentration of thyroid hormone
a. the concentration of serum T4 (normal 15-55nmol / l or 12-43ng/ml)
b. 98% of the increased risk of cats, T4 concentration 55nmol / l or 43ng/ml
c. serum T3 levels were normal bit 0.6-1.9nmol / l or 0.4-1.2ng/ml
10% -30%, hyperthyroidism in the cat, the normal concentration of T . Treatment: After 4 weeks of treatment, if the T4 continues to rise, increasing the dose 5mg per day below normal, reduce the dosage.
side effects:
- Lack of appetite, vomiting and lethargy, but without stopping.
- Itching associated with skin shedding published, required withdrawal
- Reversible liver damage
- Neutropenia, thrombocytopenia, recovery after stopping a week
- About 20% of cats 12 weeks after medication side effects.


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