have primary biliary cirrhosis

30 May

17:23 , Via Original

Abstract primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC) is unclear etiology of the rare liver disease. According to reports, PBC clusters of environmental factors may be relevant. PBC individual cases a higher incidence of thyroid disease, and has been reported to the Superfund toxic waste sites (SFS) in patients with PBC near the higher incidence of thyroid disease. The study was designed to assess the SFS individuals near the PBC and PSC the prevalence and potential clustering. Separate identification of clinical and demographic data was used to identify each zip code in New York City area (n = 174) and borough (n = 5) received liver transplantation for PBC (PBC-OLT) and PSC (PSC-OLT) patients observed prevalence. Application of Organ Procurement and Transplantation Network (OPTN) and U.S. Census data calculate the expected prevalence. PBC-OLT patients and non-registered patients who underwent liver transplantation (PBC-MSSM) is included in cluster analysis. According to SFS density approximation and compare the various zip code areas and the borough PBC-OLT and PSC-OLT cases, the prevalence ratio. SaTScan software is used to identify the PBC-OLT and PBC-MSSM cases aggregation. SFS SFS containing or adjacent postcode areas the prevalence of PBC-OLT was significantly higher ratio of (1.225 vs0.670; P = 0.025) while the prevalence of PSC-OLJ ratio unchanged. Staten Island has a high prevalence ratio of PBC-OLT and the density of SFS.
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primary biliary cirrhosis (pbc) is an autoimmune liver disease that causes progressive . however, men with pbc may have a more severe disease course and are .

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