Health Worlds

Herpes simplex virus (HSV) infection on the human body is common. It is a DNA virus. The formation of small pox herpes virus, called herpes simplex virus type I; the formation of large blisters pox virus, called herpes simplex virus type II. Occurred in oral herpes simplex infection, known as oral herpes simplex.
Primary herpetic stomatitis is the most common type I herpes simplex virus induced oral lesions. It may present as a more severe gingivostomatitis - acute herpetic gingivostomatitis, children under the age of 6 were more common, especially 6 months to 2 years more, adults are not uncommon. Often before the onset of a history of exposure, the incubation period from 4 to 7 days. Then fever, headache, fatigue discomfort, generalized muscle pain, sore throat or other acute symptoms, submandibular and neck lymph node swelling, tenderness, children salivation, poor feeding, irritability. After 1 to 2 days of prodromal period, a wide range of oral mucosa edema, attached gingiva and the gingival margin there was a marked acute inflammatory damage. Oral mucosa of any part of the cluster of small blisters are visible, the wall thin, transparent, and soon ulceration, superficial ulcers form, can cause large areas of ulceration after the erosion, and cause secondary infection. Skin around lips and mouth had a similar lesion, herpes scab crust formed after rupture. A few cases, infection can spwidely in the body, as well as causing encephalitis, meningitis, and other life


-threatening complications. Most untreated cases, slow recovery of more than 10 days.
After healing of primary herpes infection, 30% to 50% of cases of recurrent damage can occur, known as recurrent herpes stomatitis, also known as recurrent herpes labialis. Is characterized by clusters of blisters started, and the lesions are always at or near the original seizure recurrence. Recurrence of a lot of incentives, such as sunlight, local mechanical damage, cold and mild fever and other stimuli, emotional factors may also be the predisposing factors. RAU can be the precursor of a slight sense of fatigue and discomfort, and soon the local area have tingling, burning, itching, increased tension and other symptoms. About 10 hours, a blister in this area, surrounded by mild erythema. 24 hours after the rupture, erosion, crusting. Generally about 10 days healing, there is secondary infection, lesions occurring at the small pustules, healing delay. Without leaving scars after healing, but may have pigmentation. After a few days to several months, you can re-attack.
For the diagnosis of oral herpes simplex, herpes of the base material can be a direct smear, can be found in the cell damage by viruses, such as balloon-like degeneration, edema of the cells, and multinucleated giant cells, nuclear inclusions, etc., indicating a viral infection. In serum, the anti-herpes simplex virus antibody titers increased significantly.
The names of diseases (English) simple herpes virus infection Pinyin Classification of Diseases code alias Western infectious disease name Western medicine defines disease classification code for herpes simplex virus infection by herpes simplex virus (HSV) and clinical signs caused by a variety of groups Clinically, mainly for the orofacial, genital herpes and encephalitis. Release Name Western medicine is a cause of herpes simplex virus HSV Branch, a diameter of about 180-200nm, electron microscope, particles formed by the concentric multiple layers, the inner core, including strands of DNA and protein, the outer surface of the body of the protein capsid of 20 The most outer layer is coated by the fat and sugar, proteins, HSV glycoprotein antigen specificity of the decision. Chinese people who cause the season is a natural area the only of infection. Intensity and spof the disease spmainly through direct , HSV can still be a type droplets through the air, HSV a type spmainly through sex, HSV- in the delivery model can be directly infected newborn through the birth canal. The disease had no significant seasonal, with the main distribution. Pathogenesis of the virus since the incidence of skin and mucous membrane invasion in epithelial cells reproduce, leading to cell lysis and produce local inflammation, sometimes with local lymph nodes. TCM lung pathology pathophysiology of viremia, liver, brain and other body spis extremely rare. Primary infection, the virus that is along the axis into sensory ganglia, there was latent for life, and along the axon to the skin and mucous discharge of the virus cycle, when the environment changes the body, such as the occurrence of other infections, the application of adrenal cortex hormones and immunosuppressive agents such circumstances, HSV can be activated and cause recurrent infection. In normal subjects, HSV infection caused by skin and mucous membrane lesions confined to the surface. However, cellular immunity has not yet mature or functional defects, as well as more extensive skin damage, such as infant eczema or burns, then HSV infection often develop extensive mucocutaneous herpes lesions, viremia and visceral dissemination, a serious condition. Western medicine diagnosis standard diagnostic criteria for diagnosis of Western medicine diagnosis is based on the incubation period 2-12d, the average 4d. History of clinical symptoms and signs common types are as follows: orofacial infections: the initial issuance of HSV- infection is most common in children and young people, mainly in oral inflammation and pharyngitis. Patients with fever, myalgia, neck lymph nodes, herpes can affect the lips, gums, palate, and facial Sheqian Department. Rash and a burning sensation the first part of rash, followed by a blister, blister showed erosion after ulceration, dry, scab. The initial issuance of HSV- and HSV- infection can cause pharyngitis, tonsillitis, local may have ulcer. Reactivation of recurrent infection is the most common clinical manifestation of recurrent herpes labialis, often in pneumonia, meningitis, malaria and other diseases or cure most of the later. Infection in immunosuppressed persons may spto the deep mucosa and skin, and skin lesions associated with hemorrhagic necrosis.
Reproductive tract infections: HSV- and HSV- can cause genital tract infection, but type is more easily activated after infection and repeated attacks. Onset are generally in the sexual intercourse occurs around 4d after infection and urethritis reproductive tract disorders, fever, perineum around the anus, labia, cervix, penis, urethra, etc. pain, itching, 24h after the emergence of local herpes, after the collapse of about 6d break, 2 weeks scab, after healing, and dysuria, inguinal lymph nodes and other symptoms, female patients often have lower abdominal discomfort. Lesion recurrence light and short duration, usually about 1 week. Epidemiological investigations have failed to end genital HSV infection confirmed cervical cancer.
Herpetic paronychia: a finger infection, commonly found in medical workers. Risk refers to the edema, erythema, local tenderness, finger blister, fever, the medial epicondyle and the axillary lymph nodes go far. Duration of 2-3 weeks, a few patients may have recurrence.
Eye infection: conjunctivitis, corneal lesions are superficial, local edema, ulcers, with pain and affect vision. Deep lesions have retinitis and so on. Ocular HSV infection is an important cause of blindness.
Central nervous system infections: herpes simplex virus encephalitis is a common sporadic encephalitis. Newborn caused mainly by the type , acquired their infection from the mother's birth canal. Caused mainly by the adult type , and more from the trigeminal nerve or olfactory nerve reactivation of latent infection caused by invasion of the brain. Distribution of brain lesions were asymmetric to the hippocampus, temporal lobe, frontal lobe, etc. the most significant. Parenchymal bleeding, necrosis, softening and other changes. Rapid onset, fever, headache, vomiting, drowsiness, delirium and other symptoms, some patients in the short term disorientation, language barriers, the limitations of epilepsy, there are early behavioral and psychiatric disorders, phantom smell, taste, and other magic, suggesting temporal lobe damage. 70% died without treatment, early treatment left some patients have paralysis, mental disorders and other sequelae.
Immune function defect infections: measles associated with severe malnutrition in infants, such as HSV infection occurs, usually manifested visceral sp, but rarely involving the brain. Children with protruding fever, convulsions, hepatomegaly, petechiae and other high mortality. Medical electrical diagnosis of herpes simplex virus encephalitis, the EEG may show diffuse slow wave and the temporal lobe sharp waves, brain CT showed dense mass to reduce the temporal lobe, such that a relatively specific and can serve as the positioning of the brain biopsy . Diagnostic Imaging virus isolation laboratory diagnosis is confirmed by the basis of positive results. Orofacial or genital herpes, and the slurry within the brain, lung biopsy specimens can be inoculated into human diploid fibroblasts and other cultured ,1-3d appear immediately after cell disease, identified by monoclonal fluorescent antibody. Brain, lung and other tissues can also be directly detected with monoclonal fluorescent antibody virus antigen. Primary infection, the recovery increased antibody contribute to the diagnosis, but the potential there is no recurrence of the virus is activated increase of the phenomenon of antibody. Blood in urine other diagnostic cerebrospinal fluid immunological fecal histological examination certificate in Traditional Chinese Medicine Western medicine diagnosis identifying prognostic evaluation standard Western medical treatment of complications of acyclovir (ACV) is the drug of choice for the treatment of HSV can shorten the course of the disease, relief of symptoms . The blood concentration of 56% of goods by blood-brain barrier. Encephalitis and severe systemic infection intravenously every 8h once a 10mg/kg. 100mI dissolved in solution, the drop in 1-2h completed a course of 10-14d. In 1986 the United States reported by brain biopsy confirmed diagnosis in 27 cases, after treatment with acyclovir only 5 deaths, 6 months all patients in 15 cases. 4d onset of effect within the dosing were significantly better, it is clinically diagnosed as herpes simplex virus encephalitis by brain biopsy at the beginning of the product after treatment; if confirmed pathogen HSV, the treatment can continue, or may consider withdrawal. Of genital tract infection with herpes simplex virus, the U.S. Centers for Disease Control programs developed are: the first issue of the FDA generally oral, 5 times a day, every 200mg, treatment 5 to 7d. Severe symptoms intravenous drip, every 8hl times 5mg/kg, a total of 5 to 7d. repeated attacks, the daily oral dose of 5, each 200mg, total 5d. To prevent recurrent attacks, the daily oral administration of 2 to 5 times per 200mg. As Acyclovir inhibition of viral DNA synthesis through the work, so only the replication of the virus are cells play a role, but in a latent state for the role of virus-free, relapse after drug withdrawal. Local used acyclovir herpes virus can reduce the number, but can not alleviate the symptoms, it can not accelerate lesion healing. Pregnant women after the application of the safety of acyclovir has not yet confirmed, should not be used.
Vidarabine systemic treatment of HSV infections are also effective, encephalitis, severe infection and systemic application of a daily dose of 10-15mg/kg, intravenous drip, with a course 10d.
HSV eye infection in 0.1% available iodine glycosides or ribavirin (Ribavirin) eye drops.
Mucocutaneous herpes only local symptomatic treatment, to prevent secondary infection. Cervix or vagina of pregnant women can lead to neonatal herpes HSV infection, so the women about to give birth within a month, such as reproductive tract lesions or viral culture positive, with cesarean section is appropriate; of newborn infants eyes, mouth and other lesions The virus culture, antiviral treatment when necessary. Chinese Acupuncture and Chinese Medicine Integrative Medicine Massage preventive care and rehabilitation of historical research


Friends Links:Automation Control Blog
Automation Products Order Numbers