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Diffuse malignant mesothelioma
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Disease Alias: owned parts: chest clinic Section: Cardiothoracic Surgery, surgery, oncology
Signs and symptoms: fever, cough, respiratory disorders, chest pain, pleural effusion seasonal: spring, summer, autumn and winter
Symptoms and signs of diffuse malignant mesothelioma Pathological diagnosis of malignant pleural mesothelioma malignant mesothelioma although the issue remains controversial and classification of soft tissue sarcoma, but only 20% with histologically pure sarcoma malignant pleural mesothelioma, 33% to 50% of its tissue is tubular and papillary epithelial type or the other 30% of mixed epithelial and sarcoma most pathologists believe that only patients with tissue sarcoma or mixed with malignant pleural mesothelioma can be integrated special staining and electron microscopy data of the patients experienced Neo also willing to make the epithelial type of patients the diagnosis of malignant pleural mesothelioma Malignant mesothelioma in early visible in the normal or opaque visceral or parietal pleura there are many white or gray particles and nodules or thin plate with the development of tumors covered with nodular thickening of the pleural surface tumor nodules growing section extended to the four consecutive lung cysts into piece


s to make smaller pits the more affected side of the chest wall reduced in advanced tumors may involve the collapse of the diaphragm and intercostal muscles contralateral mediastinal pleura pericardium structure autopsy found that 50% of patients had blood-borne metastasis But rarely mentioned clinical Pathological anatomy of malignant mesothelioma, there are two types: a single fibrous pleural mesothelioma growth plate from the visceral pleura or the pedicle-like symptoms caused by tumor expansion and development due to their internal structure to chest compression if the early shift diagnosis can be used for surgical treatment of extensive spof this type of mesothelioma lung infiltration of violation of the diaphragm and intercostal muscle involvement by mediastinal pleura pericardium and great vessels Malignant mesothelioma of the microscope that has its own characteristics seen in the individual tumor nodules or macroscopic appearance of tumor nodules have the same variety of distinctly different composition of the malignant skin tumors Zhang histological type are epithelial-type fiber (inter- quality) and mixed epithelial tumor of three epithelial cells have a variety of different structures such as papillary, tubular, papillary epithelial cells polygonal ribbon work sheet there are many long, slender microvilli on the surface of branching into desmosomes beam elastic filaments and cell cavity (Figure 2) fiber-type cells similar to the spindle configuration with equal or elongated, egg-shaped well-developed nucleolus (Fig. 3) mixed type with both epithelial and fiber type two organizational structure from a tumor biopsy block the site from the different samples taken more like a hybrid is more Figure 2 Malignant epithelial pleural mesothelioma (left) and malignant pleural mesothelial cancer (right) Figure 3 Malignant fibrous mesothelioma Male 81 years old collagen bundles and a variety of atypical cell Patients with malignant pleural mesothelioma, more men than women (2:1) in most patients between the ages of 40 to 70 foreign patients average age 45.2 years 60 years only the first symptom of chest pain, cough and shortness of breath for the most common of about 10.2% of patients with fever and sweating 3.2% of patients with joint pain mainly v. symptoms involved the diaphragm and chest pain abdomen and the affected side can be conducted first shoulder about 50% to 60% of patients with severe shortness of breath, which a lot of bloody pleural effusion, 3 / 4 patients without large pleural effusion more severe chest pain and weight loss, some patients common cyclical low blood sugar and hypertrophic pulmonary osteoarthropathy but these indications were more common in benign mesothelioma And mixed epithelial pleural mesothelioma and pleural effusion is often accompanied by a large number of usually only a small amount of fiber types with or without pleural effusion of patients seems to be more involved epithelial supraclavicular or axillary lymph nodes and extended to the contralateral pleura and pericardium, peritoneum; fiber type more than a distant metastasis and bone metastasis Radiology Indications: Common X-ray found that pleural effusion, often accounting for 50% of the ipsilateral side of the chest lung tumor tissue was wrapped ipsilateral mediastinal side of the chest toward a smaller tumor disease without mediastinal widening advanced cardiac chest expansion of the heart shadow package exudate visible damage to soft tissue and ribs On a routine chest X-ray pleural diseases pleural effusion can be covered on the evaluation of suspected malignant pleural stromal tumor patients the most useful CT CT examination can show irregular pleural thickening with nodular pleural within the margin of increase as from other thick lesions distinguish malignant pleural mesothelioma due to fibrous tissue and tumor tissue and pleural fluid was a major split between the thickening of the lung tumor invasion, such as the crack can be expressed as pulmonary nodules usually can find lung nodules and the CT cysts of the lung was reduced the extent of the tumor and chest wall collapse (Figure 4) Figure 4 right diffuse malignant pleural mesothelioma Extension of the tumor grew from the parietal pleura into the lung fissure0.8mg/ml) thick pleural effusion than normal mesothelial cells generally contain well-differentiated or undifferentiated malignant mesothelial cells and different amounts of lymphocytes and polynuclear leukocytes as pleural fluid cytology can help make a diagnosis
Top department visits the First Affiliated Hospital, Zhejiang University School of Medicine Departments: Cardiothoracic Surgery Grade: Grade
Chinese medicine hospital in Hangzhou sections: Cardiothoracic Surgery Grade: Grade
Children's Hospital, Zhejiang University School of Medicine Departments: Cardiothoracic Surgery Grade: Grade
Red Cross Hospital of Hangzhou, Zhejiang Province Hospital of Integrated Traditional and Western sections: Cardiothoracic Surgery Grade: Grade
Chinese medicine hospital departments in Zhejiang Province: Cardiothoracic Surgery, Level: Three A-level Chinese medicine hospital in Hangzhou, the latest addition to visiting department sections: Cardiothoracic Surgery Grade: Grade
Red Cross Hospital of Hangzhou, Zhejiang Province Hospital of Integrated Traditional and Western sections: Cardiothoracic Surgery Grade: Grade
Chinese medicine hospital departments in Zhejiang Province: Cardiothoracic Surgery Grade: Grade
Children's Hospital, Zhejiang University School of Medicine Departments: Cardiothoracic Surgery Grade: Grade
Palit hospital department established in Zhejiang Province: Cardiothoracic Surgery Grade: Grade


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