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(A) of the original treatment as clear as possible causes, stop or suspected allergic sensitization drugs and life-long disabled. Encourage patients to drink more water or fluids to speed up the excretion of drugs from the body. Of the heavy metals such as arsenic, gold, etc., causing the eruption, to give and complexing agents, such as dimercapto-propanol (BAL) and heavy metal ions such as so complex and from the urine. (B) symptomatic and supportive therapy for the treatment of severe drug eruption principles for the timely rescue, hospital revenue as soon as possible. 1. Anti-shock and oxygen supply to the anaphylactic shock associated with those to be against the clock, immediately subcutaneous or intramuscular injection of epinephrine 1:1000 0.3 ~ 0.5ml. Oxygen breathing difficulties and who is, has been blocked airway laryngeal edema, may consider tracheotomy. 2. Hormones on Steveus-Johson syndrome, TEN, severe exfoliative dermatitis drug eruption and their early high-dose corticosteroids for the key life-saving measures. Amount should be sufficient to control the clinical symptoms prevail. Symptom control as soon as possible after the reduction to the withdrawal. 3. Select H1 receptor antagonist antihistamine, such as diphenhydramine per 50mg, or 20mg intramuscular injection 3 times a day, 3 to second-class, itching and swelling of the limb skin has a certain effect of mitigation. 4. Maintaining water and electrolyte balance attention to the amount of colloid or pr


otein input, if necessary, blood transfusions or plasma. 5. Prevention and treatment of infection. 6. Treatment of mucosal damage clean water available conjunctiva 3% boric acid, corticosteroid eyedrops eye drops once every 3h. 7. Local treatment of selected skin lesions without stimulation, with the convergence of conservation and the role of certain drugs, according to the characteristics of the damage treatment. (C) the treatment of drug eruption of light usually 2 to 7 days after stopping lesions can be dissipated. If systemic symptoms, can oral prednisone equivalent 20 ~ 40mg / d, the rash subsided immediately after withdrawal or reduction. There is secondary infection, systemic antibiotic treatment given. Local pure talcum powder or calamine lotion can be used to relieve itching anti-inflammatory, it is available when wet compress erosion effusion. agree (1) | to ask further questions (0) | Complaints for this answer
Hello! First of all I wish you well soon! Let me talk to you about "drug rash" problem. Patients in the treatment process, a rash on the skin, how to determine whether the drug-related rash it, that is the general skin disease or drug eruption. Mainly based on the occurrence of skin lesions, the development is in line with the general characteristics of drug eruption. 1) drug eruptions typically have the following characteristics: 1. A certain incubation period. After the first treatment usually takes for 7 - 8 days (maximum range of 4 - 20 days) after the incubation period, before re-treatment drug eruption occurred. Is a patient in the past have used a drug and produce sensitization, then repeat the treatment within minutes to hours after the rash can occur. 2. The incidence of drug eruption and its general pharmacological effects and dosage independent of the nature of the people aly in the sensitized state, even a very small dosage can cause disease. 3. Drug eruption healed, then the structure can induce a similar drug eruption, called cross-allergy. 4. Patients often other physical, chemical and biological factors are more sensitive, for example, eating fish after the patient has a history of hives or some kind of pollen every spring after inhaling a history of bronchial asthma attack or when the body is highly sensitive to the state it will have many types of drugs are allergies, a phenomenon called polyvalent allergy. 5. After the onset of each drug eruption, with the hormones, epinephrine or antihistamines to treat effectively. If you meet the above characteristics of the disease, they should be alert, or stop the medication, or go to the hospital for skin tests to further identify causative drugs, according to medical advice, the use of appropriate measures. 2) the drug can lead to drug eruptions are the following: 1. Sulfa drugs, phenytoin, phenobarbital, sodium Yang of ammonia, phenylbutazone and so easy to cause exfoliative dermatitis drug eruption. In the treatment of such drug eruption occurred after 20 days, beginning as measles, scarlet fever-like, accompanied by chills, fever, and then the whole body flushing, swelling, hand, foot and face as the weight. After the body skin desquamation, hand, foot and was glove, sock-type stripping large areas of skin, and some (toe) A, hair loss, swollen lips, erosions, conjunctival hyperemia. Associated with severe kidney, liver damage, accompanied by high fever, coma, so as to cause death. 2. Penicillin, furazolidone, sodium salicylate and serum anti-toxin and other products such as tetanus prone to urticaria-type drug eruption. Acute onset after treatment, the skin and the rapid emergence of sudden itching bright red sizes air group, were round, oval or irregular in shape, scattered in the head, face and limbs and trunk, and from diminishing this phenomenon. Heavier vomiting, fever and joint pain. Drug eruption caused by these drugs more common. 3. Antipyretic and analgesic, hypnotic, sedative drugs, iodine amine drugs, penicillin and streptomycin and other drugs can lead to fixed drug eruption and measles or scarlet fever-like drug eruption. Fixed drug eruption more common in the lips, anus, penis and other genital mucosa at the junction of the skin, limbs, trunk may also occur, skin rash for one or several sizes of circular edematous erythema, bullae may appear on erythematosus, a itch sense of burning, withdrawal or regression, such as the then serving the same medication, can occur in the original part of the same eruption, so called fixed drug eruption. Measles or scarlet fever-like drug eruption begins abruptly, with chills, fever and other symptoms. Morbilliform drug eruption of the rash is scattered or dense, needle or grain size or the rash of red rash, symmetrically distributed to the trunk as much. Small piece of scarlet fever-like drug eruption to erythema, from the face, neck, upper limbs, trunk downward. 4. Mercury agents, quinine, and sulfa drugs can cause eczema, drug eruption. As polymorphism, may have erythema, blisters, papules, pustules, erosions and exudation change. Often due to sulfa or antibiotic ointment for external use, the first skin hypersensitivity, after taking the same drugs can cause drug eruption. Improvement after drug withdrawal. Drug-induced skin damage limb performance are varied, including almost all types of skin rash. Shows the clinical manifestations of drug eruption is very complex. However, the drug eruption is not some regularity at all. For most people, an allergic reaction caused by a drug there are many similarities. Not just doctors, is the drug users themselves, as long as careful observation, in general, not difficult to find yourself on what drug allergy. In short, the drug was found abnormal skin and mucous membrane reaction to an immediate withdrawal, and to identify the cause and take measures to prevent health hazards of drug eruption. If satisfied with the answer above, please do not live up to my piece of good intentions, time on the "adopted as the answer."



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