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Disease Alias: No Information respective positions: on the rash sections: physical examination: No detailed information about the cause of metabolic acidosis caused by what? More . signs and symptoms of metabolic acidosis which performance and how to diagnose? More . Check metabolic acidosis tests which check should be done? More . differential diagnosis of metabolic acidosis and the diseases easily confused? More . complications of metabolic acidosis can be complicated by the diseases? More . metabolic acidosis, prevention and health care should be how to prevent? More . therapeutic use of metabolic acidosis should be treated? More commonly used drugs .
Metabolic acidosis: Details of human arterial blood pH (pH) is the blood concentration of the negative logarithm of H. Normal is 7.35 ~ 7.45, balance is 7.40. H in body fluid intake low. Mainly in the metabolism of endogenous from. Acid-base load of the body are well-established regulatory mechanisms, including buffer. Compensatory and corrective role. Carbonate and bicarbonate is the most important role in body fluids largest Buffer, metabolic acid load. H and HCO3-combine to form H2CO3, H2CO3 very unstable, most break down into CO2 and H2O. CO2 excreted through the breath, the blood HCO3-and H2CO3 ratio maintained at 20:1, pH values will remain unchanged, but the compensation is limited. If more than the body can compensate for the degree of acidosis will be further intensified. Metabolic acidosis is the most common


type of acid-base balance disorders. HCO3-reduced to primary (<21mmol / L) and PH levels (<7.35) for the characteristic
Metabolic acidosis is the most common type of acid-base balance disorders, is increased or extracellular HCO3-H caused by primary loss of HCO3-reduced (<21mmol / L) and PH levels (<7.35) as characteristics. Metabolic acidosis in the clinical judgments, the anion gap (AG) has important clinical value. According to different AG AG normal value can be divided into high chloride and high chloride normal AG metabolic acidosis. Metabolic acidosis caused by what? 1. High chlorine normal AG metabolic acidosis
(1) Lactic acidosis: Lactic acidosis is a common metabolic acidosis causes. Normal lactate dehydrogenase by pyruvate in lactate (LDH) under the action made by the hydrogenation NADH, NADH is transformed into NAD. Lactic acid under in LDH NAD into NADH when the time into pyruvate. Therefore decided that the main direction of the reaction of pyruvate and lactate as a reaction between the substrate concentration and the ratio of NADH and NAD situation. Normal glucose glycolysis can produce NADH, but the resulting mitochondrial NADH can be generated to the NAD, addition of pyruvate in the pyruvate dehydrogenase (PDH) into acetyl-CoA under the action of A, which then passed into the citric acid cycle CO2 and H2O (Figure 1).Under normal oxidative conditions, lactate can enter the liver or kidney mitochondria within the cell, after
Human arterial blood pH (pH) is the blood concentration of the negative logarithm of H, the normal as 7.35 ~ 7.45, balance is 7.40. Carbonate and bicarbonate is the most important role in body fluids largest Buffer, metabolic acid load, H and HCO3-combine to form H2CO3, H2CO3 very unstable, most break down into CO2 and H2O, CO2 excreted through the breath, the blood HCO3-and H2CO3 ratio maintained at 20:1, pH values will remain unchanged, But the compensation is limited, if more than the body can compensate for the degree of acidosis will be further intensified. Metabolic acidosis is the most common type of acid-base balance disorders, to primary HCO3-reduced (<21mmol / L) and PH levels (<7.35) for the features.H produced nothing more than excessive discharge blocked, or HCO3-losing too much. Common in peritonitis, shock, fever and other metabolic waste too much acid, or long-term can not eat too much fat decomposition, the accumulation of ketone bodies; diarrhea, intestinal fistula, biliary fistula and pancreatic fistula, a large number of HCO3-loss from the digestive tract; acute renal failure, row H and re-absorption of HCO3-blocked.
When H increases the body, except the role of body fluid buffer system, mainly by lung and kidney regulation. H HCO3-


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