Health Worlds

Sixth National Parkinson disease (PD) movement disorders and other academic meetings 2 June 2008 grand opening of 14 in Nanchang. Chinese Medical Association crazy credits will be movement disorders and Parkinson Diseases team of consultants Wang Xinde, Lau W, Luo Yi, Tang Xiao-fu, Liu Zhuo Lin, and Professor Liang Xiuling and Sheng-Di Chen, head of school, Professor Chen Biao attended the meeting. New Zealand's famous neurologist Anderson (Anderson), Professor and Snow (Snow) is also invited to attend the meeting, Professor Conference and made wonderful presentations. More than 150 from across the country and the Department of Neurology, Neurosurgery, MD, and research staff, graduate students attended the meeting and the genetics of Parkinson disease markers, early diagnosis and treatment, neuroprotective treatment of disease and other movement disorders clinics and other areas of special reports and in-depth exchanges. Now the main content of the meeting are summarized below. Years of change, Stars turn. From the establishment of Parkinson's Disease in 1978, since the study group, after 30 years of unremitting efforts, the study of Parkinson's disease more great wings. Professor Chen Shengdi Parkinson's disease from our basic research, clinical research, foreign exchange, the quality of published papers and research Parkinson's disease and changes in international status rein detail the history of Parkinson's disease process and the prospect of a new era. Familial Parki


nson's disease-related gene mapping, detection as well as the relationship between the pathogenesis of Parkinson's disease Parkinson's disease is one of the hot. To date, 13 causative genes have been found with the familial Parkinson's disease or Parkinson's disease is closely related syndrome, in which the -synuclein, Parkin, UCH-L1, PINK1, DJ-1, LRRK2 and ATP13A2 etc. gene mutation is more thorough. Professor Tang Beisha genes around the gene structure, function, mutation characteristics, clinical phenotype and pathogenic aspects of genetic testing routes made a presentation on the latest developments. Guo Jifeng of the early-onset autosomal recessive familial Parkinson's disease genetic testing were found of autosomal recessive early-onset Parkinson's disease mainly in the Parkin gene mutation based, and PINK1 and DJ-1 mutations are relatively rare, not detected ATP13A2 mutations. Zhang Ting analysis of autosomal dominant pedigrees exist Parkinson Asp478Tyr and Gly2385Arg LRRK2 gene mutation, found that the typical clinical features of Parkinson's disease. Parkinson's disease with dementia and standardized treatment of the mechanism is always troubled by academic problems. Professor Chen Xiaochun to cognitive impairment in Parkinson's disease clinical features, pathogenesis, and the challenges facing the standard treatment, made a detailed and systematic introduction. Liu Yue important deposit found in genes that cause Parkinson's disease PINK1 by ubiquitin - proteasome pathway (UPP) degradation, and found an important molecular chaperone protein and PINK1 CHIP interaction between the proposed UPP activity of CHIP by increasing the promotion of PINK1 degradation. Lufthansa found that gold can be induced by rotenone glyceraldehyde phosphate dehydrogenase (GA Parkinson's disease H) overexpression and aggregation, and further lead to changes in neuronal homeostasis, resulting in neuronal apoptosis, and she also explored the mechanism of protein misfolding and impact . Bear study reported rotenone in dopaminergic cells after treatment significantly increased autophagy, autophagy can be proposed as a new experimental treatment for Parkinson's disease target. Liu Kangyong reported mutant -synuclein in the outside world more easily under the action of toxin accumulation and degradation by lysosomal autophagy pathway, autophagy inducers identified potential role of anti-Parkinson's disease. D is found in centenarians with -synuclein in a higher incidence of lesions, suggesting that age and the disease-related. And Han Yan Li Huanmin respectively cerebrospinal fluid in Parkinson's disease proteomics research and neurotransmitters in Parkinson's disease changes were reported. Ni Xia County 11C labeled using positron emission tomography (11C-PET) evaluation of the severity of Parkinson's patients with different brain dopamine transporter (DAT) functional status. Study found that patients with early Parkinson's may have abnormal basal ganglia uptake, suggesting that the method could be Parkinson's disease early diagnosis and assessment of imaging markers of disease progression. Liu Weiguo details of a comprehensive international Parkinson's disease assessment scale non-motor symptoms. Xiaolei the use of the Montreal Cognitive Assessment (MoCA) Evaluation of cognitive function in Parkinson's disease and found that the scale than the mini-mental state examination (MMSE) has a higher sensitivity. Neuroprotective treatment to save through the brink of death of dopaminergic neurons in Parkinson's disease fundamentally blocking process is one of the hotspots of today's academic research, the importance of neuroprotective treatment increasingly prominent. Professor Chen Biao Chen Haibo, and new forms of drug treatment in respect of the prospect of Parkinson's disease and cell and gene therapy for Parkinson's disease progress in a special report, emphasizing the early and timely neuroprotective treatment on delaying the disease progression has a significant meaning. Professor Xu Pingyi evaluated rasagiline (rasagiline) and selegiline (selegiline) block lactacystin (lactacystin) inducing effect of dopamine neurons and found that rasagiline is not only more effective than selegiline, but also with the latter do not have the nerve repair. Jing Pan to curcumin animal model of Parkinson's disease and its mechanism of protection was reported. Wang Shaojun details of the DNA vaccine PVAX1-h -Syn on a good animal model of Parkinson's disease treatment. Song Lu reported adenosine A2a receptor antagonist in animal models can alleviate levodopa-induced motor complications.
Parkinson's disease model should follow the principle of individualized drug therapy, surgical treatment, rehabilitation, training and comprehensive treatment of the principles of Chinese medicine treatment. Professor Li Yongjie from surgery screening, target selection, process control and analysis in terms of efficacy of surgical treatment of Parkinson's disease conducted a special report. Professor Zhang Jianguo is a detailed description of the neural regulation of movement disorders in the use of value. Even the report of the Royal Zhu (Yahr ) reasonable rehabilitation of patients can significantly improve motor function. TCM treatment of Parkinson's disease emphasize diagnosis and treatment, Professor Cai Dingfang TCM from Parkinson's disease, treatment, diagnosis and treatment and other aspects of strategy and introduced the country medicine in the treatment of Parkinson's disease. In addition to Parkinson's disease, the movement of many other disorders, a lack of national standards for diagnosis and treatment guidelines. How to regulate the treatment programs for these diseases is imminent. Professor Liang Xiuling liver degeneration of the diagnosis and treatment guidelines were introduced in detail, highlighting the liver degeneration type and stage of clinical importance, and ceruloplasmin, serum copper and urinary copper in the determination of disease diagnosis and medication reference guide, but also norms of different type, stage and treatment strategy. Professor Tang Xiaofu dystonia is to diagnosis and treatment guidelines for the presentation, she pointed out that the dystonia importance of etiologic diagnosis and standardized treatment steps. Professor Sun Bomin of surgical treatment of dystonia to the presentation, the reported deep bilateral subthalamic nucleus stimulation for primary generalized dystonia, and tardive dyskinesia significant effects, proposed for the non-organic Primary systemic disease dystonia (particularly DYT1 mutation) and drug-induced tardive dyskinesia and drug with poor efficacy of deep brain stimulation as a treatment of choice for a new point of . Professor Xiao Qinfu visitors to learn more of the pathogenesis and treatment of essential tremor new progress, focused on the genetic and gene essential tremor characteristics. Throughout the current academic session, has the following distinctive features: the current academic session but it is also 30 years of cum-celebration of Parkinson's disease, Parkinson's disease concentrated scholars of the older generation of the hard work hard work, passing the old experts expectations of the younger generation, has a special historical significance; the current academic conference papers from across the country received a total of more than 150 articles, academic conferences and Parkinson's disease compared to previous, paper quality, coverage and innovation were significantly improve; chaired by the Professor Chen Shengdi "Multimedia analysis and diagnosis disease movement disorders," interactive sessions, a vivid demonstration of the movement of rare disorders; After the fifth Conference on Parkinson's disease, after the establishment of the session is still outstanding paper award to encourage outstanding young scholars.
Passing on the tradition, the older generation of scholars, hard work, a new generation of scholars with both hands the torch burning, the cause of Parkinson's disease are at an unprecedented pace into the new era. The next 30 years, must be the "gold" color 30 years. Academic integration, the platform to build, the concept of innovation, which means the brand must be started. This is the grand cause of China's blueprint for Parkinson's disease, Parkinson's disease is the cause of the firm steps towards the international arena, which is the National Parkinson's Disease scholar Zhang blood spray. TAG: Parkinson's disease pathogenesis of Parkinson's disease Parkinson's disease diagnosis of Parkinson disease treatment


Friends Links:Automation Control Blog
Automation Products Order Numbers