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Abstract cause of premature ovarian failure caused by a multi-line ovarian failure, can lead to infertility and in patients with low estrogen levels caused by a series of problems, such as delayed puberty, secondary sexual characteristics dysplasia, secondary sexual characteristics normal female development before the age of 40 persistent amenorrhea and genital atrophy, may present with matrix thermal sweating, facial flushing, low sexual desire, such as different symptoms of low estrogen levels, caused great suffering to women. Current Western medicine treatment of premature ovarian failure mainly taken hormone replacement therapy, Chinese medicine and acupuncture treatment is mainly diagnosis and treatment, hormone replacement therapy compared with Western medicine has the advantages of fewer side effects, experimental research and clinical observation showed a significant effect.
Key words ovarian failure, in the Wm.
Reof TCM treatment of early ovarian premature ovarian failure (prematureovarianfailure, POF), Department of a multi-cause ovarian failure due to the general population incidence rate of 1% to 3% of those in the menopause about 2% to 10%. The disease can lead to infertility and in patients with low estrogen levels caused by a series of problems. POF is the normal age of menarche or delayed puberty, normal female secondary sexual characteristics before the age of 40 persistent amenorrhea and genital atrophy, accompanied by follicle stimulating hormone


(FSH) and luteinizing hormone (LH) increased, while estrogen (E2) reduce the syndrome. Matrix can occur in patients with thermal sweating, facial flushing, low sexual desire, such as different degrees of low estrogen symptoms. So far, POF etiology and pathogenesis is not clear, medical education | education network collected more eggs may be due to congenital reduction in the number, the normal process of follicular atresia after birth to accelerate or destruction of eggs by different mechanisms resulting in premature depletion of follicles. Most scholars believe that the main causes of autoimmune dysfunction, chromosomal or other genetic factors, receptor abnormalities, metabolic abnormalities or drugs, radiation injury and viral infection. Although there is no premature ovarian failure of the Chinese name of disease, but according to the symptoms characteristic of the classical Chinese medicine has long been discussed, scattered in
Current location: China paper Ce Medi Clin Integrative Medicine in the body of 50 cases of premature ovarian failure
China paper Center [ ] elegant Confucianism, Wang Song Editor: studa20
3 Discussion
Thinking of 3.1 disease name EPO previously thought follicle (FSH)> 40mIU/ml, estrogen (E2) level is low, due to amenorrhea before the age of 40 diagnosed as premature ovarian failure. But now some young women prefer medical record, is a "high gonadotropin amenorrhea", about 20% of these patients surviving in the ovarian follicles of ovulatory menstrual or recoverable. Currently considered to be in normal premature ovarian decline before menopause, but it does not mean FSH increased ovarian function is not reversible, and found a variety of reasons can cause the clinical manifestations of ovarian failure in young women before the specific cause, to be called high gonadotropin hormones menopause, premature ovarian failure is more than reasonable, because the 40mIU/ml does not mean permanent failure [1]. Premature ovarian failure before the age of menopause is 40 high gonadotropin combined hyperlipidemia, Example 1 has 43-year-old patient, but the menopause before the age of 40, after treatment able to restore reproductive function, but does not necessarily prove that the disease is not reversible , so called for the proper high gonadotropin amenorrhea.
3.2 Prediction of ovarian reserve based on FSH (Section 2 refers to menstrual blood FSH level to 3 days), generally consid 20mIU/ml as abnormal [2], 10mIU/ml suggest ovarian failure may be hiding on, FSH further increased response decreased ovarian reserve of follicles. Even in the menopause status, if FSH and 183.5 pmol / L (> 50pg/ml) function within ovarian follicles suggest the existence of circulating FSH decline, combined with E2 increased the recovery of follicular activity.
3.3 The diagnostic criteria for at least two different days measured blood hormone FSH 40mIU/ml, E2 low levels (E2 <30, pg / ml), PRL normal, 40 years old on or before amenorrhea (secondary amenorrhea 6 months) or primary amenorrhea (16 years old and menstrual cramps yet) who can diagnose high gonadotropin amenorrhea (HGA), according to check for ovarian follicles, can be divided into premature ovarian failure (POF) or ovarian insensitivity syndrome (ROS). Also based on history, symptoms and signs and the auxiliary examination to make etiological diagnosis.
The most important function of the immune system is to protect the "self" and the exclusion of "self", in some pathological cases, the immune system does not recognize "self" and thus began to attack "self" immune system disease, immunity is mainly to exclude other POF known cause, and confirmed the presence of one or more autoimmune disease before diagnosis.
3.4 HGA identified disease and diagnosis and treatment, especially in patients with POF, in the past found it difficult to restore ovulation and fertility, menstruation, with the development of medicine, clinical practice has proved to combine Chinese and Western medicine treatment of particular importance. Depending on the prediction of ovarian reserve before menopause, for the cause, early treatment is not irreversible. Especially for patients with expected growth is expected to "old clam Health beads". Chinese medicine for the multi-component, multi-system, multi-link, multi-levels of overall conditioning, it is not the hormone itself, but with significant hormonal effects, no hormonal side effects, especially to improve the ovarian response to gonadotropin and ovarian hormone receptor content.
Kidney nourishing particles have to adjust the role of gonadal axis, in medicine, "kidney" function, including Western's reproductive system, endocrine system, nervous system, immune system function. In the "kidney" substantial study found that "kidney" and the gonads are closely related. Chinese Kidney - menstruation - Chong and Ren - the uterus constitutes the reproductive axis and Western medicine, the hypothalamus - pituitary - ovary - uterus gonadal axis are very similar. In the menstrual cycle it manually with traditional Chinese medicine to treat the idea of adjusting week to obtain satisfactory results.
Modern Chinese medicine theory holds that ovarian failure is a type of infertility etiology and pathogenesis of renal menstruation, Chong Ren, including due to Palace's failure. Dodder, Morinda, Cistanche, etc. can increase the pituitary, ovary, uterus weight; habitat, Ligustrum, Eclipta basis of grass in serum FSH, LH levels decreased; amethyst, angelica, cinnamon, which will enable E2, P levels increased significantly improve the ovarian reserve; Angelica, Chuanxiong, Danshen improve microcirculation, increase blood supply to the ovaries can stimulate ovulation; Millettia, medlar, Placenta, etc. of endometrial thickness can improve assisted reproductive purposes.
HGA is difficult gynecological endocrine diseases, the majority of ovarian failure of unknown cause amenorrhea or failure to restore normal ovulatory menstrual or fertility is often very difficult. I take the medicine to medicine-based healing and a son of 50 cases, mostly early, aggressive treatment of non-stop, we must be cautious in the diagnosis, so as not to cause unnecessary suffering to patients. Although Chinese medicine exposition of early menopause, but its diagnosis mainly depends on gonadotropin (Gn) determination, and to repeat many times (at least 2 times, the time interval of 7 days), to rule out the possibility of higher Gn before ovulation, combined with ultrasound on development of ovarian follicles and the situation has to make a scientific diagnosis.
Reference
1 Cheng Jing. Gynecologic difficult disease in TCM diagnosis and treatment. Beijing: People's Medical Publishing House ,2003,268:272-27
2 LANG Jing, Chen Ying Zhu. Female reproductive health and disease. Zhengzhou: Zhengzhou University Press, 2003,7 Links in the paper for


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