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Question: pulmonary heart disease in patients with chronic respiratory failure, blood gas analysis results: pH7.188, PaCO275mmHg, PaO250mmHg, HCO3-.27.6mmol / L, BE-5mmol / L, the acid-base imbalance typeC. respiratory acidosis metabolic acidosis
D. Metabolic alkalosis
E. respiratory acidosis with metabolic alkalosis
Do not understand, please explain?BE (base excess): [base excess] under standard conditions (blood temperature of 38 , oxygen saturati00%, PaCO2 40mmHg), with acid or base titration of whole blood samples to pH 7.4 when the acid or base used volume. Titration with acid, said base excess (BE), titration with alkali, said base deficit (-BE).
Normal: 0 3 mmol / L
Significance: The indicator reflects the metabolic factors. Positive value indicates the base excess negative value indicates the base deficit.
Acidosis: HCO3-/H2CO3 ratio <20 / 1, PH value decreased or lower than the normal limit of 7.3 Alkalosis: HCO3-/H2CO3 r 20 / 1, PH value is rising or higher than the upper limit of normal 7.4 Simple
Metabolic acidosis: HCO3-down due to plasma acidosis caused.
Metabolic alkalosis: Due to an increase in plasma HCO3-caused by alkalosis.
Respiratory acidosis: an increase in the PH value for H2CO3 down.
Respiratory alkalosis: the PH value decreased due to increased H2CO Medical


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Metabolic acidosis is the most common type of acid-base balance disorders, is increased or extracellular HCO3-H caused by primary loss of HCO3-reduced (<21mmol / L) and PH levels (<7.35) as characteristics. Metabolic acidosis in the clinical judgments, the anion gap (AG) has important clinical value. According to different AG AG normal value can be divided into high chloride and high chloride normal AG metabolic acidosis. Metabolic acidosis caused by what? 1. High chlorine normal AG metabolic acidosis
(1) Lactic acidosis: Lactic acidosis is a common metabolic acidosis causes. Normal lactate dehydrogenase by pyruvate in lactate (LDH) under the action made by the hydrogenation NADH, NADH is transformed into NAD. Lactic acid under in LDH NAD into NADH when the time into pyruvate. Therefore decided that the main direction of the reaction of pyruvate and lactate as a reaction between the substrate concentration and the ratio of NADH and NAD situation. Normal glucose glycolysis can produce NADH, but the resulting mitochondrial NADH can be generated to the NAD, addition of pyruvate in the pyruvate dehydrogenase (PDH) into acetyl-CoA under the action of A, which then passed into the citric acid cycle CO2 and H2O (Figure 1).Under normal oxidative conditions, lactate can enter the liver or kidney mitochondria within the cell, after
Medical HEALTH "> Clinical Abstract respiratory acidosis combined metabolic acidosis is common in what the patient? the full text of reRecommended collection of online article, "Journal of Nursing Education," 2008 Volume 23 No. 7 fast food prizes Executive Summary: A: respiratory acidosis metabolic acidosis seen in two patients: (1) acute and chronic respiratory insufficiency (obstructive pulmonary disease) patients with concurrent lactic acidosis associated with shock; (2) cardiopulmonary arrest can occur simultaneously with acute respiratory acidosis and lactic acidosis. Pages: Page 1 Page Range :629-629 Key words: acute respiratory acidosis metabolic acidosis Chronic respiratory insufficiency lactic acidosis obstructive pulmonary disease cardiopulmonary arrest occur simultaneously subject classification: R827.1 [Medicine , HEALTH "Special Med Military Medi Special Weapons Da Chemical Weapons poisoning] R589.6 [medicine, HEALTH" within SCIENCES "endocrine diseases and metabolic disor Metabolic Dise acid-base balance] Related articles: subject


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