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Anxiolytics and hypnotics class relies on clinical manifestations and treatment of signs and - Beijing Hospital, anxiolytics and hypnotics Mingshi class dependent signs and clinical manifestations and treatment - Beijing Arcadia Hospital
Beijing Malibu Heart Hospital for seven days in drug addiction addiction experts led to the abuse of periodic or continuing anti-anxiety drugs or hypnotics, psychological dependence or physical dependence on these drugs.
Hospital experts say Beijing when the Ming Shi intake later reduced to a certain extent, there will be self-limiting withdrawal syndrome. Drug resistance relatively irregular, not completely, so a lot of behavior disorders and the toxic symptoms continue, according to the duration of the pharmacokinetics of various drugs effects may be. in ethanol and barbiturates and benzodiazepines, including non-barbiturate sedative hypnotics, including between the agent will be there is some mutual , incomplete cross-resistance. (barbiturates and ethanol in the resulting dependence, withdrawal symptoms and chronic toxicity responses are very similar.)
In general, dependence on sedative and hypnotic agents are the people like the role of rapid drug (such as the Secretary may, phenobarbital, pentobarbital). Methaqualone as had been widely abused, has entered the federal class controlled drugs, in The United States has been banned. methaqualone counterfeit medicines, including anti-histamine, and sometimes large doses of diaze


pam. Jiabing urethane (meprobamate), and barbiturates as similar effects, so is not a safe sedative .Progressive signs of sedative poisoning decreased as the superficial skin reflex, nystagmus small lateral , clearly a substantial degree of mild hypothyroidism associated with rapid nystagmus, ataxia and articulate vague and posture instability. When you look into the re-transfer condition nystagmus, lethargy, ataxia and sometimes fall significantly, confusion, deep sleep, miosis, respiratory depression, leading to death. taking large doses of sedatives are often difficulties in thinking, language and understanding of the slow (dysarthria), memory is not good, bad judgments, and emotional instability and lax attention. is generally believed that, in combination slow thinking, slurred speech and limbs caused by Shuaidie Wu Qing scars suggestive of sedative dependence.
More sensitive to withdrawal effects for some patients, psychological dependence develop very rapidly, goes without a few weeks, once the withdrawal will reduce the deterioration of the original sleep again, inhibition of restlessness, frequent nightmares, and often awoke, and feel nervous in the morning. As for the physical dependence and medication is the length of time and dose related; for example, daily doses of 200mg pentobarbital even several months will not cause significant resistance, but if daily doses of 300mg, more than 3 months, then stop after drug withdrawal symptoms, and daily 500 ~ 600mg, only 1 month withdrawal reactions can occur.
Disable the high-dose barbiturate medicines suddenly have serious amazing, even life-threatening withdrawal syndrome, symptoms similar to delirium tremens. Withdrawal should be hospitalized. Once the withdrawal symptoms are often difficult to reverse, but if follow the law carefully treatment, symptoms can be reduced. rebuild the balance of the central nervous system takes about 30 days. Sometimes, even if the right 1 to 2 weeks after treatment, recurrence is still possible. In quick barbiturate withdrawal after 12 20 hours, patients treated without, will become increasingly restless, trembling weakness. The next day was shaking even more, deep tendon hyperreflexia, weakness weakness heavier. had more than a day in patients taking 800mg, 75% will 2 to 3 days convulsions convulsions. Such seizures may develop into status epilepticus, and even death. from 2 to 5 days, if not treated, withdrawal syndrome can be manifested as delirium, insomnia, confusion and the terrible visions and hearing voices, there are often fever and dehydration.
Benzodiazepine and barbiturate withdrawal syndrome similar to, but rarely so serious. As the drug stays longer in the body, so symptoms may be more slowly. According to reports, will also have to take the severity of the treatment doses were not and other withdrawal symptoms, but why large numbers of this unusual phenomenon, the reasons remain unclear. with rapid absorption and rapid decline in blood concentrations of drugs (such as alprazolam, lorazepam, triazolam) and , their withdrawal symptoms can be the most serious. abuse of benzodiazepines in many patients with drugs is a serious alcoholic, they have withdrawal symptoms more slowly and may merge occurred alcohol withdrawal. has been confirmed by the benzodiazepine antagonist flumorph Cenis (flumazenil) may be effective in treating secondary to benzodiazepine over-serious composure. As most of the excess benzodiazepine patients can recover without treatment, so clinical flumorph Seney function has not been fully elucidated. flumorph Seney for the treatment of sedation, occasionally cause convulsions.Particular barbiturate sedative treatment program is dependent on re-medication, and then re-schedule the withdrawal according to strict, while keeping watch for signs of withdrawal. Before starting the withdrawal, it should give no medicine, but also fasting fasting 200mg in patients with oral pentobarbital as a sedative drug test; if the patient did not result in drug resistance, will be at 1 to 2 hours after the sleep or drowsiness. but who will moderate a certain resistance to the sedative; can tolerate 900mg of patients without any signs of poisoning. If there is no effect of the dose of 200mg, you can repeat every 3 to 4 hours to test higher doses to test its resistance level. severe anxiety or agitation in patients with increased resistance. Once the patient can tolerate 24 hours of usage, you should give him taking this dose of pentobarbital, 4 times a day, 2 or 3 days after the day until the symptoms and stable reduction of 10%.
An alternative approach is the application of phenobarbital. It does not like the faster onset of drug that have a "stoned" feeling, but anticonvulsant medicine. Quick barbiturates and other sedative hypnotic agent, or a small number of anti-anxiety drugs, drug-dependent patients can be equivalent to the average daily dose of 1 / 3 of phenobarbital as an alternative (Table 195-2); for example, the patient had been taking before the Secretary may barbiturate 1000mg / d , then make the stability of phenobarbital dose is 300mg / d, or 75mg / 6 hours. Department of the use of oral phenobarbital, 4 times a day, reduced the initial daily dose of 30mg, the elimination of drugs until the patient dependence. As an initial daily dose is based on estimates derived from medical history, it is inevitable that error, so in the first 72 hours must pay close attention to patient response. If the patient still showed agitation or anxiety, should increase the dose; if the look drowsiness, articulate vague or nystagmus should reduce the dose. In patients with withdrawal detoxification process, to avoid the application of other sedatives or psychoactive drugs. However, if the patient is also taking antidepressants, then, should immediately stop with this antidepressant drugs (especially tricyclic antidepressants), but should be 3 to 4 days on the decline.Beijing Malibu Heart Hospital for seven days in addiction medicine drug addiction detoxification method: traditional Chinese medicine drug withdrawal. Beijing Malibu Heart Hospital for seven days in drug addiction medicine addiction treatment effects developed, timely and effective discharge of drug physical dependence and reduce the psychological dependence on drugs, and can quickly increase the body nutrition, increased drug resistance, enhanced immune function and endocrine regulation within the body related to metabolism balance. Drug
Hospital, Beijing Malibu neurotransmitter effects of Chinese medicine preparation on the adjustment disorder and recovery role. The efficacy of traditional Chinese medicine not only in the control of withdrawal symptoms, drug detoxification and for quite a long time after the memory of insomnia, anxiety, pain and other symptoms of prolonged withdrawal of treatment and rehabilitation, and long-term existence of the lifting of the drug on craving . Protracted withdrawal symptoms are one of the main causes of relapse is still difficult for Western drug problems. DrugChinese medicine treatment difference: traditional Chinese medicine treatment sedative Chufan, detoxification, rousing, pain ventilation, diuretic detoxification, replenishing spleen, quickly get through the body channel blocking, blood running smooth, so that the body natural detoxification, regulation of central nervous system disorders, intractable insomnia correct, and enhance overall immune function of the body, yin and yang, qi and blood have a balance, to fine, gas, full of God. the heart of Chinese medicine with anti-drug addiction, anxiety, rapid withdrawal, anti-relapse and other characteristics, the unique magic of Chinese medicine scientific formula, open up the human context, coordination of the autonomic nervous system, enhance blood flow, drug Walking the body, activate the body cells, heart and blood flow, speeding up metabolism, rid the body of toxic liver and kidney toxins. Completely replaced so far on the domestic and international use of a very unscientific


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