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Current location: China paper Ce Medi Clin body diagnosis and treatment of severe ulcerative colitis, the new progress
China paper Center [ ] Wu Yuli Editor: studa20
4.1.4 ASA preparations when severe ulcerative colitis after corticosteroid therapy had remission and reduction period, the addition of the drug. Mesalazine used in our hospital, the daily 4g, 4 times to swallow, 4 weeks; gradual reduction after remission, reduction of 1 every 4 weeks, and finally to a daily maintenance dose 2g, divided oral dose to maintain 3 to 5 years. Medication should be monitored regularly during the blood and liver and renal function.
4.1.5 immunosuppressant corticosteroids for treatment of poor patients. After the drug was added gradually reduced glucocorticoid dosage, or even withdrawal. Used in our hospital methotrexate, each 2.5mg, 1 day or per 5mg, 2 times per week. Medication should be regularly reed during the blood, liver and kidney function and blood drug concentration.
4.1.6 probiotics to restore the drug the ecological balance of normal flora in the gut, and indirectly enhance the amino acid active ingredient 5-ASA preparations utilization (amino acid preparations by the intestinal bacteria in the colon is divided into 5 - ASA). This drug treatment can make the whole body and local regulation of intestinal T cells (Tr) change. CD 4CD 25Tr ratio in peripheral blood and spleen decreased, increased in the colon. CD 8CD-28Tr the opposite [6].
4.1.7 enema treatmen


t of severe ulcerative colitis patients depending on the circumstances, retention enema may be given before going to bed. Agents commonly used in our hospital: Compound Bletilla solution (from agents), rehabilitation of new ,5-ASA enemas, steroid enemas agent, treatment 1 to 3 months.
4.2 Surgical treatment for complicated bleeding, intestinal perforation, toxic colon expansion of medical therapy and in patients with severe sepsis. So far, in our hospital are valid medical treatment in severe cases.
4.3 Chinese medicine treatment of medical diagnosis and treatment according to the motherland with temporary and permanent two laws, and enhance a patient's own immune function, so as to achieve the purpose of treatment. In addition, acupuncture or massage therapy has a certain effect.
4.4 qigong and other bio-behavioral approach Qigong is a traditional health practices, through the ideas of adjustment in the induction and atmosphere play a role in self-regulation, so as to achieve enhanced patient's own immune function.
5 standard cure
Recent cure: Clinical symptoms disappeared, normal colonic mucosa remirror, just to maintain the amount of drugs for 6 months without recurrence. Effective: Basic symptoms, colonoscopy resome of mucosal inflammation and mild off polyp formation. Invalid: After treatment, clinical symptoms, endoscopic and pathological examination no improvement.
Ulcerative colitis of unknown etiology and pathogenesis of complex, heavy with poor prognosis of ulcerative colitis, ulcerative colitis so early diagnosis and treatment is extremely important. Based on typical clinical manifestations, colonoscopy, diagnosis is not difficult to set up. The key is to control the treatment of acute attack, prevention of complications. In the method based on the medical treatment, integrated treatment. In recent years, with the pathophysiology of ulcerative colitis and the progress made in molecular biology, and promoted the development of drug treatment, to patients with ulcerative colitis has also brought new hope. With the constant awareness of the disease, but also will make new advances in treatment, is expected to improve the prognosis of patients with ulcerative colitis.
Reference
1 Ren-gao Ye, Zai-Ying Lu. Internal Medicine, 5th Edition. Beijing: People Health Press ,2001,428-43
2 Russel MG.Changes in the incidence of inflammatory bowel disease: What does it mean? Eur J Intern Med ,1-19
3 Jiang XL, Cui HF. An analysis of 10 218 ulcerative colitis cases in China. World J Gastroenterol, 8-16
4 Wang Xiaodi, Wu Tie-yong, Han Chunli. Endoscopic features of ulcerative colitis and clinical analysis. Beijing Medical Journal, 2006,28 (6): 325-32
5 Yang Xuesong, Yao Wei, Liu Wenbin, et al. Heavy ulcerative colitis Clinical features and treatment outcomes. Chinese Journal of Digestion, 2006, 26 (5): 291-29
6 Ning, especially Peng, Liu Annan, et al. Probiotics in the treatment of experimental colitis the role of regulatory T cells. Chinese Journal of Digestion, 2006, 26 (2) :100-103. Reposted elsewhere in the paper for free http
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